Virtual Reality Exposure Therapy in Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients

Status: Recruiting
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). Participants are randomly assigned to one of the following interventions: a) exposure condition - the group with a standard CBT program enriched with exposure therapy in VR (VRET), b) control condition 1 - the group with a standard CBT program enriched with VR cognitive training aimed at cognitive flexibility or c) control condition 2 - standard CBT program without any additional VR intervention. The treatment effect will be evaluated using pre/post assessments, as well as monitoring adherence to exposure and response prevention assignments.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 17
Maximum Age: 55
Healthy Volunteers: f
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• Diagnosis of OCD (F42) using currently valid DSM-V and ICD-11

• Fluent in Czech

Contact Information
Primary
Iveta Fajnerová
Iveta.fajnerova@nudz.cz
+420-608501034
Backup
Pavla Stopková
Pavla.stopkova@nudz.cz
Time Frame
Start Date: 2022-11-15
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 62
Treatments
Experimental: Virtual reality exposure
Participants complete 6-week CBT program with five 30-40-minute sessions of exposure administered via a virtual reality headset (once a week). The intervention involves exposure to various symptom provoking scenarios in the virtual house environment - OCD house. Scenarios can be adjusted to distinct OCD dimensions: contamination/cleaning, fear-of-harm/checking, symmetry/ordering. Stimuli can be also freely combined across dimensions, so that the scenarios fit to individual needs.
Active_comparator: Cognitive flexibility training
Control group attends 6-week CBT program with five sessions of 30-40 minutes of cognitive training via virtual reality headset using VRcity cognitive training games.
Active_comparator: Standard CBT without additional VR treatment
Control group completes the standard 6-week CBT program only, with no VR sessions.
Related Therapeutic Areas
Sponsors
Leads: National Institute of Mental Health, Czech Republic

This content was sourced from clinicaltrials.gov