Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

The bidirectional link between sleep and pain is a widely accepted concept. While there has been much focus on this in recent years, studies investigating obstructive sleep apnoea (OSA) and chronic pain are still not very common, especially in context of continuous positive airway pressure (CPAP) therapy. In this study, people recently diagnosed with OSA, a common sleep disorder, that are receiving a CPAP mask are asked to fill in questionnaires at baseline, 3- and 6-month follow-up. Data of people with and without chronic pain will be collected and we will use the data will allow us to answer a number of clinically relevant questions. The primary questions investigate the following: 1) The association of CPAP adherence and pain outcomes with CPAP therapy at 3-month follow-up; 2) The association of baseline Apnoea-Hyopnea-Index on pain outcomes with CPAP therapy at 3-month follow-up. Secondary questions investigate the relevance of co-morbid insomnia (COMISA), the influence of chronic pain on CPAP adherence and general clinical outcomes of CPAP therapy in people with chronic pain.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Participants must be 18 years of age or older

• Participants must be able to read and write in Dutch, French or English

• Participants must be diagnosed with clinically relevant OSA and newly start CPAP treatment:

• AHI ≥ 15

• Prescribed CPAP for the first time as a treatment for their OSA

• Participants must have read and signed the ICF

Locations
Other Locations
Belgium
Universitair Ziekenhuis Brussel
RECRUITING
Brussels
Contact Information
Primary
Nils Runge, MSc
nils.arno.andreas.runge@vub.be
+32 2 477 44 20
Backup
Olivier Mairesse, PhD
Olivier.mairesse@vub.be
+32 2 629 25 16
Time Frame
Start Date: 2025-03-10
Estimated Completion Date: 2026-04
Participants
Target number of participants: 80
Treatments
CPAP group
People defined as obstructive sleep apnoea with or without chronic pain. They undergo standard care (CPAP therapy).
Related Therapeutic Areas
Sponsors
Leads: Vrije Universiteit Brussel

This content was sourced from clinicaltrials.gov