Learn About Oligodendroglioma

View Main Condition: Brain Tumor

What is the definition of Oligodendroglioma?
Oligodendroglioma is a type of brain tumor that develops from oligodendrocytes, which are specialized cells that protect neurons (nerve cells). Oligodendroglioma can occur in the brain and spinal cord.  Oligodendrogliomas are also classified as either Grade 2 or Grade 3. Grade 2 oligodendrogliomas do not spread as aggressively as Grade 3 and are less likely to cause severe symptoms.
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What are the causes of Oligodendroglioma?
The cause of oligodendrogliomas is still unknown. However, oligodendrogliomas generally tend to be more common in adults than children. Men are also more likely to develop oligodendrogliomas than women.
What are the symptoms of Oligodendroglioma?
Symptoms for oligodendroglioma primarily depend on the size and location of the tumor. Common symptoms include seizures, headaches, short-term memory issues, personality changes, and weakness on one side of the body.
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What are the current treatments for Oligodendroglioma?
Treatment for oligodendroglioma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove the tumor is generally the first step in treating oligodendroglioma. Depending on the tumor's location, surgery may be able to entirely remove smaller oligodendrogliomas. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of oligodendrogliomas. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
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What is the outlook (prognosis) for Oligodendroglioma?
The prognosis for oligodendroglioma is very good with current treatments. When the tumor can be removed, survival rates are over 90%. If the tumor can not be removed but radiation therapy is used, survival rates are between 80-90%.
How do I prevent Oligodendroglioma?
There is no known way to prevent oligodendrogliomas. However, if you develop any symptoms common to oligodendroglioma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Oligodendroglioma Clinical Trials?
Phase II Trial of Niraparib in Patients With Recurrent Glioma

Summary: The purpose of this study is to determine what effects (good and bad) niraparib has on patients with recurrent brain cancer.

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A Pilot Study of Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Summary: By employing a combination of advanced MRI techniques and correlative serum biomarkers of blood brain barrier (BBB) disruption, the investigators plan to develop a powerful, first of its kind clinical algorithm in pediatrics whereby the investigators can measure and identify the window of maximal BBB disruption post MLA to 1) allow for an alternative to surgery in incompletely resected tumors, 2) ...

What are the Latest Advances for Oligodendroglioma?
Current Considerations in the Treatment of Grade 3 Gliomas.
Laser Interstitial Thermal Therapy in Grade 2/3 IDH1/2 Mutant Gliomas: A Preliminary Report and Literature Review.
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Extraventricular neurocytoma at the sellar region: Report of 8 cases and literature review.
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Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.