Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications: Efficacy and Safety Outcomes.
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
The purpose of this study is to investigate the efficacy of three different modalities of post-operative pain control in parturient with opioid use disorders. The investigators aim to determine whether the different approach utilized show better outcomes with pain management and if there are any association with reduction of symptoms of anxiety, depression, and overall well-being.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:
• Inclusion criteria include being a parturient with Substance use disorder (SUD) and age 18-35
Locations
United States
Wisconsin
Froedtert Hospital
NOT_YET_RECRUITING
Milwaukee
Froedtert Hospital Milwaukee, Wisconsin 53226
RECRUITING
Milwaukee
Contact Information
Primary
Meredith Albrecht, MD, PhD
maalbrecht@mcw.edu
414-805-8700
Backup
Christopher Fadumiye, MD
cfadumiye@mcw.edu
414-805-8700
Time Frame
Start Date: 2025-01-16
Estimated Completion Date: 2028-12
Participants
Target number of participants: 20
Treatments
Active_comparator: Transverse abdominal Plane(TAP) Block with long acting Exparel
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Active_comparator: Postoperative Epidural infusion for 24-36hrs
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Active_comparator: Hydromorphone Patient Controlled Analgesia (PCA),Preservative free Morphine via epidural for 36hrs
A subset of participants (n=15) will be divided into three different arms: A.) Postoperative Epidural infusion for 24-36hrs B.) Hydromorphone Patient Controlled Analgesia (PCA) with Preservative free Morphine via epidural for 36hrs C.) Transverse abdominal Plane(TAP) Block with long acting Exparel.
Related Therapeutic Areas
Sponsors
Leads: Medical College of Wisconsin