Oppenheim DystoniaSymptoms, Doctors, Treatments, Advances & More
Learn About Oppenheim Dystonia
View Main Condition: Movement Disorders
Early-onset isolated dystonia is one of many forms of dystonia, which is a group of conditions characterized by involuntary tensing of the muscles (muscle contractions), twisting of specific body parts such as an arm or a leg, rhythmic shaking (tremors), and other uncontrolled movements. An isolated dystonia is one that occurs without other abnormal movements or other neurological symptoms, such as seizures, a loss of intellectual function, or developmental or intellectual delay. Early-onset isolated dystonia does not affect a person's intelligence.
A particular variant (also called a mutation) in the TOR1A gene (also known as DYT1) is responsible for most cases of early-onset isolated dystonia. Variants in other genes cause other forms of dystonia, such as dystonia 6.
Early-onset isolated dystonia is among the most common forms of childhood dystonia. This disorder occurs most frequently in people of Ashkenazi (central and eastern European) Jewish heritage, affecting 1 in 3,000 to 9,000 people in this population. The condition is less common among people with other backgrounds. It is estimated to affect 1 in 10,000 to 30,000 non-Jewish people worldwide.
Variants in the TOR1A gene are inherited in an autosomal dominant pattern, which means one of the two copies of the gene is altered in each cell. Many people who have a variant in this gene are not affected by the disorder and may never know they have the altered gene. Only 30 to 40 percent of people who inherit a TOR1A gene variant will ever develop signs and symptoms of early-onset isolated dystonia.
Atrium Health Neurology Specialty Care, A Facility Of Carolinas Medical Center
Danielle Doggett is a Neurologist practicing medicine in Charlotte, North Carolina. Dr. Doggett is rated as an Advanced provider by MediFind in the treatment of Oppenheim Dystonia. She is also highly rated in 19 other conditions, according to our data. Her clinical expertise encompasses Parkinson's Disease, Movement Disorders, Essential Tremor, Drug Induced Dyskinesia, and Deep Brain Stimulation. Dr. Doggett is board certified in American Board Of Psychiatry And Neurology. Dr. Doggett is currently accepting new patients.
Movement Disorders-Neurology
Marcie Rabin is a Neurologist practicing medicine in Livingston, New Jersey. Dr. Rabin is rated as an Elite provider by MediFind in the treatment of Oppenheim Dystonia. She is also highly rated in 14 other conditions, according to our data. Her clinical expertise encompasses Oppenheim Dystonia, X-Linked Dystonia-Parkinsonism, Drug Induced Dyskinesia, and Myoclonus-Dystonia. Dr. Rabin is currently accepting new patients.
Swedish Neuroscience Specialists - Movement Disorders
Movement disorders are most effectively treated by adopting a multidisciplinary approach and closely collaborating with the patient, the family and other caregivers. Every member of the clinical team is invaluable in delivering high-quality, high-value care to patients and their families. Dr. Khemani is the Medical Director of the Movement Disorders Program within the Swedish Neuroscience Institute. Dr. Khemani is rated as an Experienced provider by MediFind in the treatment of Oppenheim Dystonia. He is also highly rated in 23 other conditions, according to our data. His clinical expertise encompasses Movement Disorders, Parkinson's Disease, Essential Tremor, Deep Brain Stimulation, and Orchiectomy. Dr. Khemani is board certified in American Board Of Psychiatry And Neurology. Dr. Khemani is currently accepting new patients.
Published Date: April 22, 2022
Published By: National Institutes of Health