Oral Squamous Cell Carcinoma Overview

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Learn About Oral Squamous Cell Carcinoma

What is the definition of Oral Squamous Cell Carcinoma?
Oral squamous cell carcinoma is the most common mouth cancer (95%). Oral squamous cell carcinoma can develop in any part of the mouth, including the lips, gums, tongue, inner lining of the cheeks, roof of mouth, and floor of mouth. Oral squamous cell carcinoma can spread (metastasize) to other areas of the head and neck.
What are the symptoms of Oral Squamous Cell Carcinoma?
Symptoms of oral squamous cell carcinoma may include a sore on the lip or mouth that does not heal, a sore that bleeds, a white or reddened patch inside the mouth, loose teeth, a lump or other growth in the mouth, neck lump, mouth and ear pain, a change in speech, and difficulty swallowing.
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What are the current treatments for Oral Squamous Cell Carcinoma?
Treatment for oral squamous cell carcinoma depends on the affected area and stage of the mouth cancer and may include surgery, radiation therapy, chemotherapy, targeted drug therapy (cetuximab), immunotherapy, reconstructive surgery, dental implants, and speech and occupational rehabilitation. Individuals with oral squamous cell carcinoma should quit smoking or other tobacco products and drinking alcohol. After treatment, individuals who have had oral squamous cell carcinoma will need regular follow-up to check for cancer recurrence.
Who are the top Oral Squamous Cell Carcinoma Local Doctors?
Elite in Oral Squamous Cell Carcinoma
Koh-ichi Nakashiro
Elite in Oral Squamous Cell Carcinoma
Koh-ichi Nakashiro
Toon, JP 

Koh-ichi Nakashiro practices in Toon, Japan. Nakashiro is rated as an Elite expert by MediFind in the treatment of Oral Squamous Cell Carcinoma. Their top areas of expertise are Oral Squamous Cell Carcinoma, Candida Infection of the Skin, Head and Neck Squamous Cell Carcinoma (HNSCC), and Adenoid Cystic Carcinoma.

Elite in Oral Squamous Cell Carcinoma
Luiz P. Kowalski
Elite in Oral Squamous Cell Carcinoma
Luiz P. Kowalski
Head And Neck Surgery Department, 
Sao Paulo, SP, BR 

Luiz Kowalski practices in Sao Paulo, Brazil. Mr. Kowalski is rated as an Elite expert by MediFind in the treatment of Oral Squamous Cell Carcinoma. His top areas of expertise are Oral Squamous Cell Carcinoma, Salivary Gland Tumors, Head and Neck Squamous Cell Carcinoma (HNSCC), Thyroidectomy, and Laryngectomy.

 
 
 
 
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Elite in Oral Squamous Cell Carcinoma
Jun Sato
Elite in Oral Squamous Cell Carcinoma
Jun Sato
Ishikari, JP 

Jun Sato practices in Ishikari, Japan. Mr. Sato is rated as an Elite expert by MediFind in the treatment of Oral Squamous Cell Carcinoma. His top areas of expertise are Oral Squamous Cell Carcinoma, Osteonecrosis, Cerebral Hypoxia, Osteomyelitis, and Bone Marrow Aspiration.

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What are the latest Oral Squamous Cell Carcinoma Clinical Trials?
Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy
Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy
Enrollment Status: Recruiting
Publish Date: September 23, 2025

Summary: Investigating the Relationship Between Oral Microbiome Alterations and Tumor Markers in Locally Advanced Oral Squamous Cell Carcinoma (LA-OSCC) After Neoadjuvant Chemoimmunotherapy: Implications for Therapeutic Efficacy, Chemoresistance, and Prognostic Assessment

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Neoadjuvant Low-Dose Radiotherapy Combined With Adebrelimab and Single-Agent Albumin-Bound Paclitaxel Chemotherapy for Early-Stage Oral Squamous Cell Carcinoma: A Prospective, Single-Arm Clinical Trial
Neoadjuvant Low-Dose Radiotherapy Combined With Adebrelimab and Single-Agent Albumin-Bound Paclitaxel Chemotherapy for Early-Stage Oral Squamous Cell Carcinoma: A Prospective, Single-Arm Clinical Trial
Enrollment Status: Recruiting
Publish Date: June 27, 2025
Intervention Type: Drug
Study Phase: Phase 2

Summary: This is a prospective, single-arm, Phase II clinical trial. The included population consisted of untreated patients with histologically confirmed stage I-II oral squamous cell carcinoma. Eligible patients received neoadjuvant low-dose radiotherapy combined with adibelizumab and monotherapy with albumin paclitaxel for two cycles. Radical surgical resection is planned to be carried out 3 to 4 weeks ...

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