Orbital Pseudotumor

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Orbital Pseudotumor?

Orbital pseudotumor is the swelling of tissue behind the eye in an area called the orbit. The orbit is the hollow space in the skull where the eye sits. The orbit protects the eyeball and the muscles and tissue that surround it. Orbital pseudotumor does not spread to other tissues or places in the body.

What are the alternative names for Orbital Pseudotumor?

Idiopathic orbital inflammatory syndrome (IOIS)

What are the causes for Orbital Pseudotumor?

The cause is unknown. It mostly affects young women, although it can occur at any age.

What are the symptoms for Orbital Pseudotumor?

Symptoms may include:

  • Pain in eye, and it may be severe
  • Restricted eye movement
  • Decreased vision
  • Double vision
  • Eye swelling (proptosis)
  • Red eye (rare)

What are the current treatments for Orbital Pseudotumor?

Mild cases may go away without treatment. More severe cases most often respond well to corticosteroid treatment. If the condition is very bad, the swelling may put pressure on the eyeball and damage it. Surgery may be needed to remove part of the bones of the orbit to relieve the pressure.

What is the outlook (prognosis) for Orbital Pseudotumor?

Most cases are mild and outcomes are good. Severe cases may not respond well to treatment and there may be some loss of vision. Orbital pseudotumor most often involves only one eye.

What are the possible complications for Orbital Pseudotumor?

Severe cases of orbital pseudotumor may push the eye forward so much that the lids cannot cover and protect the cornea. This causes the eye to dry out. The cornea may become cloudy or develop an ulcer. Also, the eye muscles may not be able to properly aim the eye which can cause double vision.

When should I contact a medical professional for Orbital Pseudotumor?

People with this condition need regular follow-up care with an eye doctor who is familiar with the treatment of orbital disease.

Call your provider right away if you have any of the following problems:

  • Irritation of the cornea
  • Redness
  • Pain
  • Decreased vision


McNab AA. Orbital infection and inflammation. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 12.14.

Wang MY, Rubin RM, Sadun AA. Ocular myopathies. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, PA: Elsevier; 2019:chap 9.18.

Yanoff M, Cameron JD. Diseases of the visual system. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 423.

Latest Research

Latest Advance
  • Condition: Orbital Pseudotumor
  • Journal: Cancer investigation
  • Treatment Used: Radiotherapy
  • Number of Patients: 20
  • Published —
This study evaluated outcomes after radiotherapy for patients with orbital pseudotumor.

Clinical Trials

There are no recent clinical trials available for this condition. Please check back because new trials are being conducted frequently.