What is the definition of Osmotic Diuresis?

Osmotic diuresis is increased urination due to the presence of certain substances in the fluid filtered by the kidneys. This fluid eventually becomes urine. The process of osmosis created by these substances cause additional water to come into the urine, increasing its amount.

What are the causes for Osmotic Diuresis?

Osmotic diuresis can be caused by:

• High blood sugar (glucose)
• Use of certain medicines, such as Mannitol

REFERENCES

Kamel KS, Halperin ML. Interpretation of electrolyte and acid-base parameters in blood and urine. In: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner and Rector's The Kidney. 11th ed. Philadelphia, PA: Elsevier; 2020:chap 24.

Pfennig CL, Slovis CM. Electrolyte disorders. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 117.