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Functional Muscle-Bone Incongruity Index (FKUI): Combined Evaluation of Handgrip Strength, Total Hip Bone Mineral Density, and Lumbar-Hip Bone Mineral Density Discordance in Adults Undergoing DXA

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age 18 years or older

• Attendance at the Physical Medicine and Rehabilitation outpatient clinic

• Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation

• Ability to perform handgrip strength testing

• Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis

• Ability and willingness to provide written informed consent

Locations
Other Locations
Turkey
Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey
RECRUITING
Küçükçekmece
Contact Information
Primary
Dilek Ün Oğuzhanasiltürk, MD
dilekunoguzhan@gmail.com
+90 5056367184
Time Frame
Start Date: 2026-05-01
Estimated Completion Date: 2027-05-01
Participants
Target number of participants: 200
Treatments
Adults Undergoing Bone Mineral Density Evaluation
Adult patients attending the Physical Medicine and Rehabilitation outpatient clinic and undergoing routine DXA assessment as part of clinical evaluation. Participants will undergo handgrip strength measurement and assessment of bone mineral density parameters. The Functional Muscle-Bone Incongruity Index (FKUI) will be evaluated using handgrip strength, total hip bone mineral density, and lumbar-hip bone mineral density discordance. No treatment or interventional procedure will be administered.
Related Therapeutic Areas
Sponsors
Leads: Kanuni Sultan Suleyman Training and Research Hospital

This content was sourced from clinicaltrials.gov