Ovarian Cancer Clinical Trials

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Use of CA125 and Complementary Biomarkers for the Early Detection of Ovarian Cancer in Low Risk Women

Status: Recruiting
Location: See all (12) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical research study is to find out if combining a standard blood test (CA-125) that checks for ovarian cancer with other blood tests that check for related tumor markers may be helpful in the early detection of ovarian cancer in women who are at low risk. Tumor markers are substances in the blood that may be related to ovarian cancer.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 50
Maximum Age: 74
Healthy Volunteers: t
View:

• Female, \>/= 50 years old or less than 75 years old.

• Postmenopausal (\>/= 12 months amenorrhea).

• Have at least one ovary.

• Cancer-free and have not received any chemotherapy or radiation therapy for \>/=12 months prior to enrolling on this study.

• Willingness to return for CA 125 blood tests annually or earlier if indicated.

• Willingness to return to undergo transvaginal ultrasound if indicated.

• Women need to provide the name of a gynecologist or qualified healthcare professional willing to provide appropriate follow-up care if indicated

Locations
United States
Florida
Sylvester Comprehensive Cancer Center, Univ of Miami Miller School of Medicine
RECRUITING
Miami
Iowa
John Stoddard Cancer Center
RECRUITING
Des Moines
Minnesota
University of Minnesota
RECRUITING
Minneapolis
New Jersey
Carol G. Simon Cancer Center / Atlantic Health
RECRUITING
Morristown
New York
University of Rochester Medical Center
RECRUITING
Rochester
Oklahoma
University of Oklahoma Health Sciences Center
RECRUITING
Oklahoma City
Rhode Island
Women's and Infant's Hospital
RECRUITING
Providence
Texas
The University of Texas at Austin
ACTIVE_NOT_RECRUITING
Austin
University of Texas (UT) Southwestern Medical Center
ACTIVE_NOT_RECRUITING
Dallas
University of Texas MD Anderson Cancer Center
RECRUITING
Houston
Women's Hospital of Texas, Obstetrics and Gynecology Associates (OGA)
RECRUITING
Houston
UT Health Science Center San Antonio
RECRUITING
San Antonio
Contact Information
Primary
Gwen H. Corrigan
gcorriga@mdanderson.org
713-563-1790
Backup
Study Coordinator MD Anderson
713-563-6728
Time Frame
Start Date: 2001-07-02
Estimated Completion Date: 2028-11-30
Participants
Target number of participants: 8000
Treatments
Experimental: CA 125 Analysis
Experimental: CA-125 Analysis~Experimental: CA-125, HE4, and Osteopontin bio-marker analysis. Participants will have blood (3-4 tablespoons) drawn for CA-125 and other tumor markers.~Depending on CA-125 level and other tumor markers:~Blood (3-4 tablespoons) drawn for CA-125 testing and other tumor markers in 1 year.~Blood (3-4 tablespoons) drawn for CA-125 testing and other tumor markers in 3 months, OR~Blood (3-4 tablespoons) drawn for CA-125 testing and other tumor markers, and a transvaginal ultrasound in 6 weeks +/- 2 weeks.
Related Therapeutic Areas
Sponsors
Leads: M.D. Anderson Cancer Center
Collaborators: National Cancer Institute (NCI), Golfers Against Cancer

This content was sourced from clinicaltrials.gov