A RCT Comparing the Effectiveness of a Combination Therapy of Lezra and Clomid Versus Lezra Alone for Inducing Ovulation in Women Diagnosed With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and letrozole combined.Mature follicles and endometrial thickness will be checked by transvaginal ultrasound and results will be recorded.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 20
Maximum Age: 40
Healthy Volunteers: t
View:
• women of 20-40 years with a history of PCOS and resistant to CC
Locations
Other Locations
Pakistan
HIT Hospital
RECRUITING
Rawalpindi
Contact Information
Primary
Rukhsana Shaheen Afzal, MBBS,FCPS
dr_rukh2006@yahoo.com
03339014943
Backup
Tahira Jabeen, MBBS,FCPS
03121519011
Time Frame
Start Date: 2024-06-07
Estimated Completion Date: 2025-03
Participants
Target number of participants: 42
Treatments
Experimental: group 1
clomiphene citrate and letrozole combination
Experimental: group 2
letrozole alone
Related Therapeutic Areas
Sponsors
Leads: HITEC-Institute of Medical Sciences