Effects of Levocarnitine and Myoinositol in Comparison to Myoinositol Alone on Hormonal and Insulin ResistanceParameters in Subfertile Women With Insulin Resistant Polycystic Ovary Syndrome

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Dietary supplement, Combination product
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if combination of levocarnitine and myoinositol works better than myoinositol alone on insulin resistance and hormonal parameters in subfertile women with insulin resistant polycystic ovary syndrome . It will also learn about the safety of drug levocarnitine and myoinositol. The main questions it aims to answer are: Does combined action of levocarnitine and myoinositol improve insulin resistance and hormonal parameters in comparison to myoinositol alone in subfertile women with insulin resistant polycystic ovary syndrome ? What medical problems do participants have when taking drug levocarnitine and myoinositol? Researchers will compare the drug combination of levocarnitine and myoinositol to myoinositol alone to see if combination therapy works better? Participants will: Take drug levocarnitine and myoinositol or a myoinositol alone twice daily for 3 months Visit the clinic once after 3 months for checkups and tests Keep a diary of their symptoms and the number of times.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:

• 1\. Age:18-40 years old. 2. Diagnosed cases of PCOS patients(both old \& new cases) according toInternational evidence-based guideline criteria 2023, 3. Primary or secondary subfertility. 4. Insulin resistance (HOMA-IR \>2.6)(Bhowmik et al., 2016)

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Locations
Other Locations
Bangladesh
Bangladesh Medical University
NOT_YET_RECRUITING
Dhaka
Bangladesh Medical University
RECRUITING
Dhaka
Contact Information
Primary
Mst.Sumyara Khatun, MS
sumirmc09@gmail.com
+8801746046581
Backup
Mst Rebeka sultana, MBBS
drrebeka39bcs@gmail.com
+8801752011780
Time Frame
Start Date: 2025-09-19
Estimated Completion Date: 2027-03-01
Participants
Target number of participants: 72
Treatments
Experimental: Experimental arm:( Levocarnitine and myoinositol)
Participants will receive levocarnitine 330mg and myoinositol 750mg twice daily for 3 months
Active_comparator: Active Comparator (Myoinositol)
Participants will receive myoinositol 750mg twice daily for 3 months
Sponsors
Leads: Mst.Sumyara Khatun

This content was sourced from clinicaltrials.gov