Learn About Palindromic Rheumatism

What is the definition of Palindromic Rheumatism?
"Palindromic rheumatism (PR) is a type of recurrent arthritis characterized by episodes or ""attacks"" of joint inflammation, sequentially affecting one to several joint areas for hours to days. A PR attack often occurs suddenly without any obvious triggers or warning symptoms. Any joint(s) may be affected, but finger joints, wrists, and knees are most commonly affected. Symptoms during episodes may include pain, swelling, stiffness, and redness in and around the joints. Some people may have a fever and other systemic symptoms. Between episodes, people with PR have no symptoms. The time between episodes may last from days to months. The underlying cause of PR is not known. Some people with PR eventually develop chronic rheumatic disease, the most common being rheumatoid arthritis (RA). Others may develop lupus and/or other systemic disorders. People with anti-CCP antibodies detected in a blood test appear more likely to develop RA. There has been some evidence to support that PR can be a presenting feature of RA (or part of the spectrum of RA), rather than a distinct condition."
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What are the alternative names for Palindromic Rheumatism?
  • Palindromic rheumatism
  • Hench's syndrome
  • Hench-Rosenberg syndrome
  • Palindromic rheumatism syndrome
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What are the latest Palindromic Rheumatism Clinical Trials?

Summary: The main objective of this trial is to test the hypothesis that abatacept can reduce the progression of rheumatoid arthritis in ACPA+ or RF+ patients with palindromic rheumatism compared with patients treated with hydroxychloroquine.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Palindromic Rheumatism?
Efficacy of leflunomide in the treatment of palindromic rheumatism.
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Treatment of palindromic rheumatism: A systematic review.