Gemcitabine and Nab-paclitaxel Venous Injection Plus Transcatheter Arterial Infusion to Patients With Advanced Pancreatic Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The purpose of this study is to evaluate the efficacy of gemcitabine and nab-paclitaxel venous injection plus transcatheter arterial infusion to Patients with Advanced Pancreatic Cancer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
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• Ability to understand and the willingness to sign a written informed consent document.

• Age ≥ 18 years and ≤ 80 years.

• Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

• Histologically or cytologically confirmed advanced pancreas adenocarcinoma.

• Primary pancreatic cancer without major anti-cancer treatments.

• Locally advanced, or metastatic pancreatic cancer.

• Presence of at least of one measurable lesion in agreement to RECIST criteria.

• The expected survival ≥ 3 months.

• Adequate organ performance based on laboratory blood tests.

• Patients who are willing or able to comply with study procedures.

Locations
Other Locations
China
Shanghai Cancer Center
RECRUITING
Shanghai
Contact Information
Primary
Ying Yang, MD
yangying@fudanpci.org
86 64175590
Backup
Guopei Luo, MD
luoguopei@fudanpci.org
Time Frame
Start Date: 2024-03-01
Estimated Completion Date: 2028-01-01
Participants
Target number of participants: 30
Treatments
Experimental: gemcitabine and nab-paclitaxel venous injection plus transcatheter arterial infusion
nab-paclitaxel (120 mg per square meter of body-surface area) followed by gemcitabine (1000 mg per square meter) on days 1 (venous injection), 8 (venous injection), and 15 (transcatheter arterial infusion) every 4 weeks.
Related Therapeutic Areas
Sponsors
Leads: Fudan University

This content was sourced from clinicaltrials.gov