Chemotherapy and Irreversible Electroporation (IRE) in the Treatment of Advanced Pancreatic Adenocarcinoma
Who is this study for? Adult patients with Pancreatic Cancer
What treatments are being studied? Irreversible Electroporation
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
Compare the efficacy and tolerability of IRE in combination with either FOLFIRINOX or gemcitabine in patients with locally advanced pancreatic cancer.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• greater than or equal to 18 years of age
• diagnosed with stage III pancreatic cancer
• tumor is measurable
• GFR \> mL/min/1.73m2
• willing and able to comply with protocol requirements
• AST/ALT \>3 times upper limit of normal
• stable surgical post-operative course as defined by operative surgeon
Locations
United States
Kentucky
University of Louisville
RECRUITING
Louisville
Contact Information
Primary
Robert Martin, MD, PhD
robert.martin@louisville.edu
502-629-3355
Time Frame
Start Date: 2018-05-30
Estimated Completion Date: 2027-07-31
Participants
Target number of participants: 20
Treatments
Other: Treatment
Irreversible electroporation and treatment with either FOLFIRINOX or Gemcitabine (based upon which chemotherapy regimen received prior to IRE)
Related Therapeutic Areas
Sponsors
Leads: University of Louisville