Comparative Study Between Immediate Surgery Versus Neoadjuvant Chemotherapy for Management of Resectable Pancreatic Cancer
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
This trial aimed to determine whether neoadjuvant chemoradiotherapy improves overall survival compared with upfront surgery, both followed by adjuvant chemotherapy in patients with resectable and borderline resectable pancreatic cancer.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Computed tomography (CT) with pancreatic protocol + vascular mapping
• Histopathologically proven malignant by CT-guided or endoscopic ultrasound (EUS)-guided biopsy Resectable pancreatic cancer means no contact of the tumor with the Superior mesenteric artery, Celiac axis \& Common hepatic artery, and contact of the tumor but ≤90° contact with the superior mesenteric vein \& portal vein.
Locations
Other Locations
Egypt
Minia University
RECRUITING
Minya
Contact Information
Primary
Abdelrahman M Salah, MD
Abdelrahman.salah@mu.edu.eg
00201064746493
Time Frame
Start Date: 2025-02-01
Estimated Completion Date: 2026-02-01
Participants
Target number of participants: 30
Treatments
Immediate surgery group
Patients will undergo upfront surgery, then adjuvant chemotherapy.
Neoadjuvant chemotherapy group
Patients will undergo neoadjuvant chemotherapy, then surgery.
Related Therapeutic Areas
Sponsors
Leads: Minia University