Conversion Surgery for Locally Unresectable Pancreatic Cancer - International Multi-center Observational Trial (ROBIN= suRgery for lOcally unresectaBle pancreatIc Cancer)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients treated at expert centers.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients older than 18 years
• Patients able to give informed consent
• Histologically confirmed pancreatic adenocarcinoma
• LAPC stage according to NCCN10 at diagnosis (Figure 1)
• Received at least 4 months of induction chemotherapy
• RECIST 1.1 stable disease (SD) or partial response (PR) after induction therapy
• Patient considered eligible for radical resection by local MDT
Locations
Other Locations
Italy
UOC Chirurgia Generale 2, Azienda Ospedale di Padova, Padova, Italy 35128
RECRUITING
Padua
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 150
Related Therapeutic Areas
Sponsors
Collaborators: University of Padova
Leads: Azienda Ospedaliera di Padova