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Multimodal Prehabilitation Prior to Pancreatic Cancer Surgery: A Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical study is to test whether a structured prehabilitation program can be successfully used by adults with pancreatic cancer who are receiving chemotherapy before planned surgery. Prehabilitation is a program designed to improve a person's physical fitness, nutrition, and symptom control before surgery. The study's main hypothesis is that patients with pancreatic cancer can take part in and adhere to a multimodal prehabilitation program during chemotherapy, and that doing so may improve physical function, patient experience, and early recovery after surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years

• Diagnosis of pancreatic ductal adenocarcinoma (PDAC)

• Planned neoadjuvant chemotherapy prior to planned surgical resection

• Medically stable and cleared to participate in physical activity/exercise programming

• Able to provide informed consent

• Ability to read, write and understand English

Locations
United States
Massachusetts
UMass Memorial Medical Center
RECRUITING
Worester
Contact Information
Primary
Kayla R Widdowson, MD
kayla.widdowson@umassmed.edu
774-641-1257
Backup
James M Lindberg, MD
james.lindberg@umassmemorial.org
508-334-5220
Time Frame
Start Date: 2026-03-31
Estimated Completion Date: 2028-12
Participants
Target number of participants: 20
Treatments
Experimental: Multimodal Prehabilitation Program
Participants in this single-arm study will receive a structured prehabilitation program during neoadjuvant chemotherapy prior to planned pancreatic cancer surgery.
Related Therapeutic Areas
Sponsors
Collaborators: Pancreatic Cancer Alliance
Leads: University of Massachusetts, Worcester

This content was sourced from clinicaltrials.gov