Preliminary Evaluation of Screening for Pancreatic Cancer in Patients with Inherited Genetic Risk
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The study is a prospective, observational study evaluating the utility of endoscopic ultrasound or MRI for the identification of preneoplastic and neoplastic pancreatic lesions in patients at high risk for pancreatic cancer, specifically those with BRCA1/2, ATM, or PALB2 mutations.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \>= 18
• Documented germline pathogenic or likely pathogenic BRCA1, BRCA2, ATM, or PALB2 mutation
• If no history of PDAC in a first or second degree relative, age \>= 50
• If there is a history of PDAC in a first or second degree relative, minimum age of eligibility is 10 years younger than the age of onset of the youngest relative with pancreatic cancer
Locations
United States
Pennsylvania
Abramson Cancer Center of the University of Pennsylvania
RECRUITING
Philadelphia
Contact Information
Primary
Bryson Katona, MD
Bryson.Katona@pennmedicine.upenn.edu
Time Frame
Start Date: 2015-05
Estimated Completion Date: 2030-05
Participants
Target number of participants: 200
Authors
Related Therapeutic Areas
Sponsors
Leads: Abramson Cancer Center at Penn Medicine