David J. Hackam
Experienced in Pancreatoblastoma

Dr. David J. Hackam

General Surgery
Johns Hopkins Medicine
Rubenstein Child Health Building
200 North Wolfe Street, Rubenstein BLDG Lower Level, Rubenstein BLDG Lower Level, 
Baltimore, MD 

Experienced in Pancreatoblastoma
Johns Hopkins Medicine
Rubenstein Child Health Building
200 North Wolfe Street, Rubenstein BLDG Lower Level, Rubenstein BLDG Lower Level, 
Baltimore, MD 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

David J. Hackam, M.D., Ph.D., is the Garrett Family Professor of Pediatric Surgery at The Johns Hopkins University, and Pediatric Surgeon-in-Chief and co-Director of the Johns Hopkins Children’s Center. Dr. Hackam’s clinical practice focuses on complex neonatal surgery. As pediatric surgeon in chief and co-director of the Childrens Center, Dr. Hackam oversees all perioperative clinical operations that involve children, with a strong emphasis on quality and safety, programmatic growth, and system alignment. Dr. Hackam's research is focused on unraveling the mechanisms of necrotizing enterocolitis, which is the leading cause of death in premature infants from gastrointestinal disease. His work has identified a series of novel pathways that, in response to the abnormal microflora that characterizes the premature intestine, leads to intestinal mucosal barrier breakdown, bacterial translocation, mesenteric vasoconstriction, and NEC. In seeking to translate these findings to clinical studies, we have developed a family of molecules that can prevent NEC development, and which have in part been licensed for clinical development. In additional work, Hackam has developed a prototype artificial intestine, derived from patient-specific intestine stem cells, which we have implanted into pre-clinical models, for the treatment of short bowel syndrome, a devastating complication of NEC. Finally, using single-cell RNA-seq and cell tracking technology, Hackam has worked towards understanding and treating NEC-associated brain injury, a major complication of NEC, and has engineered nanoparticle-packaged molecules that can cross the blood-brain barrier, and reverse the processes that lead to this disease. These studies are funded by three ro1s, a T32, a MIRA (a maximizing investigators’ research award) and 3 industry grants from companies with an interest in NEC treatment and prevention. Dr. Hackam seeks to work with industry partners, as well as nurses, doctors, and families of patients around the country, in order to develop novel regimens to safely and effectively deliver appropriate nutrition to the most vulnerable infants, who are at risk for the development of intestinal disease.

Dr. Hackam is rated as an Experienced provider by MediFind in the treatment of Pancreatoblastoma. His top areas of expertise are Necrotizing Enterocolitis, Necrosis, Short Bowel Syndrome, Pancreaticoduodenectomy, and Hepato-Pancreato-Biliary Surgery.

His clinical research consists of co-authoring 125 peer reviewed articles. MediFind looks at clinical research from the past 15 years. In particular, he has co-authored 1 article in the study of Pancreatoblastoma.

Graduate Institution
University Of Toronto Temerty Faculty Of Medicine, Cell Biology, PhD, 1998
Residency
University of Toronto Health, General Surgery, 2000
Specialties
General Surgery
Licenses
Pediatric Surgery in MD
Board Certifications
American Board Of Surgery
Fellowships
Children's Hospital of Pittsburgh of UPMC, Pediatric Surgery, 2002
Languages Spoken
English
Gender
Male

Insurance

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
CareFirst
  • HMO
  • POS
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
First Health
  • INSURANCE PLAN
  • MEDICARE PDP
  • PPO
Geisinger
  • HMO
  • POS
  • PPO
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
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Locations

Rubenstein Child Health Building
200 North Wolfe Street, Rubenstein BLDG Lower Level, Rubenstein BLDG Lower Level, Baltimore, MD 21287
Call: 410-955-5210

Additional Areas of Focus

Dr. Hackam has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Necrotizing Enterocolitis
Short Bowel Syndrome

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


125 Total Publications

Mechanisms and consequences of NEC-induced brain injury in premature infants: understanding a silent affliction.
Mechanisms and consequences of NEC-induced brain injury in premature infants: understanding a silent affliction.
Journal: Pediatric research
Published: July 16, 2025
View All 125 Publications
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Jin He, M.D., Ph.D., is a professor of surgery at the Johns Hopkins University School of Medicine and is the Division Chief of Hepato-Pancreato-Biliary & Gastrointestinal Surgical Oncology. Dr. He specializes in diseases and tumors of the pancreas, liver, bile duct, and gallbladder. He performs open as well as minimally invasive (robotic and laparoscopic) surgery, including the Whipple procedure. Dr. He received his medical degree from Beijing Medical University and a Ph.D. in oncology from Fudan University Shanghai Medical College. He completed the Halsted general surgery residency training at Johns Hopkins, followed by an ACGME accredited fellowship in complex general surgical oncology at Johns Hopkins. Dr. He is the John Cameron Professor of Alimentary Tract Diseases. Dr. He’s research focuses on personalized treatment through stratifying pancreatic tumors on their genetic features. He holds several patents in anti-cancer vascular targeting agents and has published extensively in peer-reviewed journals and lectured internationally. He serves on several national committees, including the NCCN panel on neuroendocrine tumors and the Alliance for Clinical Trials in Oncology. Dr. He is rated as an Elite provider by MediFind in the treatment of Pancreatoblastoma. His top areas of expertise are Pancreatic Cancer, Neuroendocrine Tumor, Cholangiocarcinoma (Bile Duct Cancer), Pancreaticoduodenectomy, and Pancreatectomy.

John L. Cameron
Advanced in Pancreatoblastoma
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Advanced in Pancreatoblastoma
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General Surgery

Johns Hopkins Outpatient Center

601 North Caroline Street, Floor 8, Floor 8, 
Baltimore, MD 
 (1.2 miles away)
443-997-1508
Languages Spoken:
English
See accepted insurances

Dr. Cameron has had a long and distinguished career in alimentary tract diseases and specifically in pancreatic cancer. He has won worldwide acclaim for mastering the Whipple procedure. At the beginning of his career, the mortality rate from the Whipple procedure was nearly 30 percent. He has worked to lower that to 1 percent to 2 percent at Johns Hopkins. He has operated on more patients with pancreatic cancer and done more Whipple resections than any other surgeon in the world. In addition to maintaining a busy practice that focuses mainly on pancreatic surgery, he has been a leader in the surgical profession, serving as president of the American College of Surgeons, Society for Surgery of the Alimentary Tract, Southern Surgical Association, Society of Clinical Surgery, Society of Surgical Chairmen, Halsted Society and American Surgical Association. He served as chief of surgery for The Johns Hopkins Hospital for nineteen years. Dr. Cameron obtained his undergraduate degree from Harvard University in 1958, and his medical degree from The Johns Hopkins University School of Medicine in 1962. All of his training in General and Thoracic Surgery was obtained at The Johns Hopkins Hospital. Dr. Cameron is rated as a Distinguished provider by MediFind in the treatment of Pancreatoblastoma. His top areas of expertise are Pancreatic Cancer, Pancreatic Ductal Adenocarcinoma, Pancreatic Islet Cell Tumor, Pancreaticoduodenectomy, and Pancreatectomy.

VIEW MORE PANCREATOBLASTOMA DOCTORS

Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Hackam's expertise for a condition
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  • Elite
  • Necrosis
    Dr. Hackam is
    Elite
    . Learn about Necrosis.
    See more Necrosis experts
  • Necrotizing Enterocolitis
    Dr. Hackam is
    Elite
    . Learn about Necrotizing Enterocolitis.
    See more Necrotizing Enterocolitis experts
  • Distinguished
  • Short Bowel Syndrome
    Dr. Hackam is
    Distinguished
    . Learn about Short Bowel Syndrome.
    See more Short Bowel Syndrome experts
  • Advanced
  • Metastatic Insulinoma
    Dr. Hackam is
    Advanced
    . Learn about Metastatic Insulinoma.
    See more Metastatic Insulinoma experts
  • Experienced
  • Bile Duct Cysts
    Dr. Hackam is
    Experienced
    . Learn about Bile Duct Cysts.
    See more Bile Duct Cysts experts
  • Childhood Pancreatitis
    Dr. Hackam is
    Experienced
    . Learn about Childhood Pancreatitis.
    See more Childhood Pancreatitis experts
  • Hepato-Pancreato-Biliary Surgery
    Dr. Hackam is
    Experienced
    . Learn about Hepato-Pancreato-Biliary Surgery.
    See more Hepato-Pancreato-Biliary Surgery experts
  • Lysosomal Acid Lipase De���������������������������������������������������������������������������������ciency
    Dr. Hackam is
    Experienced
    . Learn about Lysosomal Acid Lipase De���������������������������������������������������������������������������������ciency.
    See more Lysosomal Acid Lipase De���������������������������������������������������������������������������������ciency experts
  • Pancreatectomy
    Dr. Hackam is
    Experienced
    . Learn about Pancreatectomy.
    See more Pancreatectomy experts
  • Pancreaticoduodenectomy
    Dr. Hackam is
    Experienced
    . Learn about Pancreaticoduodenectomy.
    See more Pancreaticoduodenectomy experts
View All 9 Experienced Conditions
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