Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma
This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC). Eligible adults undergo remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI dissection on the dominant side, followed by ultrasound-guided radiofrequency ablation (RFA) of a ≤7 mm contralateral focus during the same anesthesia. Outcomes include structural-recurrence-free survival, endocrine-function preservation, safety, and quality of life over 24 months.
• Age 18-65 years.
• Dominant-side PTC ≤1.5 cm suitable for endoscopic resection.
• Contralateral nodule ≤7 mm located ≥2 mm from posterior capsule.
• No radiologic lymph-node metastasis on contralateral side.
• Written informed consent.