Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC). Eligible adults undergo remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI dissection on the dominant side, followed by ultrasound-guided radiofrequency ablation (RFA) of a ≤7 mm contralateral focus during the same anesthesia. Outcomes include structural-recurrence-free survival, endocrine-function preservation, safety, and quality of life over 24 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Age 18-65 years.

• Dominant-side PTC ≤1.5 cm suitable for endoscopic resection.

• Contralateral nodule ≤7 mm located ≥2 mm from posterior capsule.

• No radiologic lymph-node metastasis on contralateral side.

• Written informed consent.

Locations
Other Locations
China
Fujian Medical University Union Hospital
RECRUITING
Fuzhou
Contact Information
Primary
Bo Wang Professor, MD
wangbo@fjmu.edu.cn
+13959123550
Time Frame
Start Date: 2018-06-01
Estimated Completion Date: 2028-06-30
Participants
Target number of participants: 60
Treatments
Experimental: Hybrid Endoscopic Hemithyroidectomy + Same-Session Contralateral RFA
Remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI central-neck dissection on the dominant lobe, immediately followed-under the same anesthesia-by ultrasound-guided radiofrequency ablation (17-G, 0.7 cm active tip, 40 W, moving-shot technique) of a ≤ 7 mm contralateral papillary thyroid microcarcinoma.
Sponsors
Leads: Fujian Medical University

This content was sourced from clinicaltrials.gov