Thyroid Cancer
Symptoms, Doctors, Treatments, Advances & More

Learn About Thyroid Cancer

What is the definition of Thyroid Cancer?

Thyroid cancer is a cancer that starts in the thyroid gland. The thyroid gland is located in the front of your lower neck.

What are the alternative names for Thyroid Cancer?

Tumor - thyroid; Cancer - thyroid; Nodule - thyroid cancer; Papillary thyroid carcinoma; Medullary thyroid carcinoma; Anaplastic thyroid carcinoma; Follicular thyroid cancer

What are the different types of Thyroid Cancer?
What are the causes of Thyroid Cancer?

Thyroid cancer can occur in people of any age.

Radiation to the thyroid increases the risk of developing thyroid cancer. Exposure may occur from:

  • Radiation therapy to the neck (especially in childhood)
  • Radiation exposure from nuclear plant disasters

Other risk factors are a family history of thyroid cancer and chronic goiter (enlarged thyroid). Being overweight or having obesity may be a risk factor for papillary carcinoma of the thyroid.

There are several types of thyroid cancer:

  • Anaplastic carcinoma (also called giant and spindle cell cancer) is the most dangerous form of thyroid cancer. It is rare, and spreads quickly.
  • Follicular carcinoma is more likely to come back and spread.
  • Medullary carcinoma is a cancer of non-thyroid hormone-producing cells that are normally present in the thyroid gland. This form of thyroid cancer tends to occur in families.
  • Papillary carcinoma is the most common type, and it usually affects women of childbearing age. It spreads slowly and is the least dangerous type of thyroid cancer.
What are the symptoms of Thyroid Cancer?

Symptoms vary depending on the type of thyroid cancer, but may include:

  • Cough
  • Difficulty swallowing
  • Enlargement of the thyroid gland
  • Hoarseness or changing voice
  • Neck swelling
  • Thyroid lump (nodule)
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What are the current treatments for Thyroid Cancer?

Treatment depends on the type of thyroid cancer. Treatment of most thyroid cancer types is effective if diagnosed early.

Surgery is most often the initial treatment. All or part of the thyroid gland may be removed. If your provider suspects that the cancer has spread to lymph nodes in the neck, these will also be removed. If some of your thyroid gland remains, you will need follow-up ultrasound and possibly other studies to detect any regrowth of thyroid cancer.

Radiation therapy may be done with or without surgery. It may be performed by:

  • Taking radioactive iodine by mouth
  • Aiming external beam (x-ray) radiation at the thyroid

After treatment for thyroid cancer, you must take thyroid hormone pills for the rest of your life. The dosage is usually slightly higher than what your body needs. This helps keep the cancer from coming back. The pills also replace the thyroid hormone your body needs to function normally.

If the cancer does not respond to surgery or radiation, and has spread to other parts of the body, chemotherapy or targeted therapy may be used. These are only needed by a small number of people.

Who are the top Thyroid Cancer Local Doctors?
Elite in Thyroid Cancer
Surgical Oncology | General Surgery
Elite in Thyroid Cancer
Surgical Oncology | General Surgery

New York University

550 1st Ave, 
New York, NY 
Languages Spoken:
English

Kepal Patel is a Surgical Oncologist and a General Surgeon in New York, New York. Dr. Patel is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. His top areas of expertise are Thyroid Cancer, Follicular Thyroid Cancer, Papillary Thyroid Cancer, Thyroidectomy, and Parathyroidectomy.

Marcia S. Brose
Elite in Thyroid Cancer
Elite in Thyroid Cancer

Jefferson Torresdale Hospital

10800 Knights Road, 
Philadelphia, PA 
Languages Spoken:
English
Accepting New Patients

Marcia Brose is an Oncologist in Philadelphia, Pennsylvania. Dr. Brose is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. Her top areas of expertise are Thyroid Cancer, Medullary Thyroid Carcinoma, Papillary Thyroid Cancer, and Anaplastic Thyroid Cancer. Dr. Brose is currently accepting new patients.

 
 
 
 
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Elite in Thyroid Cancer
Endocrinology
Elite in Thyroid Cancer
Endocrinology

UT MD Anderson Cancer Center

210 Ashville Ave # 408, 
Cary, NC 
Languages Spoken:
English
Offers Telehealth

Ramona Dadu is an Endocrinologist in Cary, North Carolina. Dr. Dadu is rated as an Elite provider by MediFind in the treatment of Thyroid Cancer. Her top areas of expertise are Anaplastic Thyroid Cancer, Thyroid Cancer, Medullary Thyroid Carcinoma, Papillary Thyroid Cancer, and Thyroidectomy.

What are the support groups for Thyroid Cancer?

You can ease the stress of illness by joining a cancer support group. Sharing with others who have common experiences and problems can help you not feel alone.

What are the possible complications of Thyroid Cancer?

Complications of thyroid cancer may include:

  • Injury to the voice box and hoarseness after thyroid surgery
  • Low calcium level from accidental removal of the parathyroid glands during surgery
  • Spread of the cancer to the lungs, bones, or other parts of the body
When should I contact a medical professional for Thyroid Cancer?

Contact your provider if you notice a lump in your neck.

How do I prevent Thyroid Cancer?

Awareness of risk (such as previous radiation therapy to the neck) can allow earlier diagnosis and treatment.

Sometimes, people with family histories and genetic mutations related to medullary thyroid cancer will have their thyroid gland removed to prevent cancer.

What are the latest Thyroid Cancer Clinical Trials?
Phase I Dose Escalation Study of Systemically Administered IL13Ra2 Chimeric Antigen Receptor (CAR) T Cells After a Nonmyeloablative Conditioning Regimen in Patients With Metastatic Melanoma and Other Solid Tumors

Summary: This phase I trial studies the side effects and best dose of modified immune cells (IL13Ralpha2 CAR T cells) after a chemotherapy conditioning regimen for the treatment of patients with stage IIIC or IV melanoma or solid tumors that have spread to other places in the body (metastatic). The study agent is called IL13Ralpha2 CAR T cells. T cells are a special type of white blood cell (immune cells) ...

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The Uptake of Radioactive Iodine Before and After a Low Iodine Diet in Patients With Differentiated Thyroid Carcinoma

Summary: The goal of this clinical trial is to compare the difference in thyroid uptake of a low dose radioactive iodine (10 MBq 123-I or 37 MBq 123-I) in athyreotic patients with differentiated thyroid carcinoma before and after a low iodine diet (LID) of 7 days. The main question it aims to answer is: • What is the difference in iodine uptake before and after a LID of 7 days? Uptake of a low dose of 123-...

Who are the sources who wrote this article ?

Published Date: February 28, 2024
Published By: Sandeep K. Dhaliwal, MD, board-certified in Diabetes, Endocrinology, and Metabolism, Springfield, VA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Kitahara CM, Pfeiffer RM, Sosa JA, Shiels MS. Impact of overweight and obesity on US Papillary Thyroid Cancer Incidence Trends (1995-2015). J Natl Cancer Inst. 2020;112(8):810. PMID: 31638139 pubmed.ncbi.nlm.nih.gov/31638139/.

National Cancer Institute website. Thyroid cancer treatment (PDQ) - health provisional version. www.cancer.gov/cancertopics/pdq/treatment/thyroid/HealthProfessional. Updated April 11, 2024. Accessed May 7, 2024.

Pearce EN, Hollenberg AN. Thyroid. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 207.

Suh I, Sosa JA. Thyroid. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. St Louis, MO: Elsevier; 2022:chap 37.

Thompson LDR. Malignant neoplasms of the thyroid gland. In: Thompson LDR, Bishop JA, eds. Head and Neck Pathology. 3rd ed. Philadelphia, PA: Elsevier; 2019:chap 25.