Latest Advances

  • Condition: Paronychia and Granulation with Chronic Lymphocytic Leukemia
  • Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology
  • Treatment Used: Silver Nitrate Chemical Cauterization with Ibrutinib Therapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with paronychia and granulation that is undergoing ibrutinib therapy for chronic lymphocytic leukemia.
  • Condition: Plexiform Neurofibroma
  • Journal: BMC pediatrics
  • Treatment Used: Selumetinib
  • Number of Patients: 3
  • Published —
This case report describes 3 children with plexiform neurofibroma that were treated using selumetinib.
  • Condition: Nevoid Melanoma and Eruptive Nevi
  • Journal: Dermatology online journal
  • Treatment Used: Erlotinib
  • Number of Patients: 1
  • Published —
This case report discusses a woman with metastatic lung cancer in remission treated with erlotinib, who experienced adverse cutaneous reactions and developed eruptive nevi and a nevoid melanoma.
  • Condition: Plexiform Neurofibromas (PN)
  • Journal: Paediatric drugs
  • Treatment Used: Selumetinib
  • Number of Patients: 9
  • Published —
This study evaluated the use of selumetinib to treat pediatric patients with inoperable plexiform neurofibromas (PN). Patients were monitored for side effects and tumor growth for an average of 12 months.
  • Condition: Inoperable Plexiform Neurofibromas
  • Journal: The New England journal of medicine
  • Treatment Used: Selumetinib
  • Number of Patients: 50
  • Published —
This study tested the safety and efficacy of using selumetinib to treat patients with inoperable plexiform neurofibromas.
  • Condition: Advanced Non-small-cell Lung Cancer
  • Journal: Cancer science
  • Treatment Used: Dacomitinib
  • Number of Patients: 81
  • Published —
The study researched the use of dacomitinib in treating advanced non-small cell lung cancer.
  • Condition: Onychogryphosis of Hand Nails
  • Journal: Joint diseases and related surgery
  • Treatment Used: Total Matricectomy and Dorsal V-Y Advancement Flap
  • Number of Patients: 18
  • Published —
The study researched the outcomes of total matricectomy and dorsal V-Y advancement flap for treating onychogryphosis of hand nails.
  • Condition: Fungal infections of the toenails
  • Journal: The Cochrane database of systematic reviews
  • Treatment Used: Topical and device-based treatments
  • Number of Patients: 12501
  • Published —
The study researched the effects of topical and device-based treatments for fungal infections of the toenails.
  • Condition: Recalcitrant Trametinib-Induced Paronychia in Pediatric Patient
  • Journal: Dermatologic therapy
  • Treatment Used: Topical Beta Blocker Treatment, Topical Timolol
  • Number of Patients: 1
  • Published —
This case report describes the first case treated with topical timolol for a trametinib-induced paronychia in a pediatric patient that allowed to continue the third line antineoplastic therapy for his glioma.
  • Condition: HER2-positive breast cancer
  • Journal: Cancer chemotherapy and pharmacology
  • Treatment Used: Pertuzumab and trastuzumab
  • Number of Patients: 48
  • Published —
The study researched the incidence of infections and hypogammaglobulinemia treated with the combination of pertuzumab and trastuzumab.
  • Condition: Patients with EGFR Mutation-Positive Non-Small-Cell Lung Cancer (NSCLC)
  • Journal: Lung cancer (Amsterdam, Netherlands)
  • Treatment Used: Low Starting Dose of Afatinib as First-Line Treatment
  • Number of Patients: 46
  • Published —
This study assessed the effectiveness and safety of low starting dose of afatinib with dose modification according to its toxicity in patients with EGFR mutation-positive non-small-cell lung cancer (NSCLC).
  • Condition: Korean Patients With Non-Small Cell Lung Cancer (NSCLC)
  • Journal: Cancer research and treatment : official journal of Korean Cancer Association
  • Treatment Used: Osimertinib
  • Number of Patients: 66
  • Published —
This study evaluated the safety and effectiveness of osimertinib in Korean patients with non-small cell lung cancer (a type of lung cancer; NSCLC).
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