Learn About Partial Seizure

What is the definition of Partial Seizure?

All seizures are caused by abnormal electrical disturbances in the brain. Focal seizures occur when this electrical activity is in a limited area of the brain. Sometimes the seizures stay only in one part of the brain, while at other times, the seizures can turn into bilateral tonic clonic seizures, which affect the whole brain. This is called secondary generalization.

Focal seizures can be divided into whether they affect awareness or not:

  • Focal, aware
  • Focal, awareness impaired

Focal seizures are also classified by whether they are motor (movements with the seizures) or not.

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What are the alternative names for Partial Seizure?

Jacksonian seizure; Seizure - partial (focal); Temporal lobe seizure; Epilepsy - partial seizures; Partial (focal) seizure

What are the causes of Partial Seizure?

Partial seizures are the most common type of seizure in people 1 year and older. In people older than 65 who have blood vessel disease of the brain or brain tumors, partial seizures are very common.

What are the symptoms of Partial Seizure?

People with focal, awareness impaired seizures may or may not remember any or all of the symptoms or events during the seizure.

Depending on where in the brain the seizure starts, symptoms can include:

  • Abnormal muscle contraction, such as abnormal head or limb movements
  • Staring spells, sometimes with repetitive movements such as picking at clothes or lip smacking
  • Eyes moving from side to side
  • Abnormal sensations, such as numbness, tingling, crawling sensation (like ants crawling on the skin)
  • Hallucinations, seeing, smelling, or sometimes hearing things that are not there
  • Abdominal pain or discomfort
  • Nausea
  • Sweating
  • Flushed face
  • Dilated pupils
  • Rapid heart rate/pulse

Other symptoms may include:

  • Blackout spells, periods of time lost from memory
  • Changes in vision
  • Sensation of déjà vu (feeling like current place and time have been experienced before)
  • Changes in mood or emotion
  • Temporary inability to speak
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What are the current treatments for Partial Seizure?

Treatment for partial focal seizures includes medicines, changes in lifestyle for adults and children, such as activity and diet, and sometimes surgery. Your doctor can tell you more about these options.

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What are the latest Partial Seizure Clinical Trials?
Genetics of Epilepsy and Related Disorders

Summary: Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to disorders related to epilepsy. These findings may help explain the broad spectrum of clinical characteristics and outcomes seen in people with epilepsy.

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An Initial Clinical Study to Treat Postictal Symptoms

Summary: This study will evaluate the effect of ibuprofen or nifedipine on post-seizure hypoperfusion and neurological deficits in patients with epilepsy. One group will receive ibuprofen, another will receive nifedipine, and anther placebo.

What are the Latest Advances for Partial Seizure?
Assessment of the long-term efficacy and safety of adjunctive perampanel in adolescent patients with epilepsy: Post hoc analysis of open-label extension studies.
Characterization and management of facial angiofibroma related to tuberous sclerosis complex in the United States: retrospective analysis of the natural history database.
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Stiripentol add-on therapy for drug-resistant focal epilepsy.
Who are the sources who wrote this article ?

Published Date: January 23, 2022
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Abou-Khalil BW, Gallagher MJ, Macdonald RL. Epilepsies. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 100.

Kanner AM, Ashman E, Gloss D, et al. Practice guideline update summary: efficacy and tolerability of the new antiepileptic drugs I: treatment of new-onset epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology. 2018;91(2):74-81. PMID: 29898971 pubmed.ncbi.nlm.nih.gov/29898971/.

Wiebe S. The epilepsies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 375.