Learn About Patent Foramen Ovale

What is the definition of Patent Foramen Ovale?

Patent foramen ovale (PFO) is a hole between the left and right atria (upper chambers) of the heart. This hole exists in everyone before birth, but most often closes shortly after being born. PFO is what the hole is called when it fails to close naturally after a baby is born.

What are the alternative names for Patent Foramen Ovale?

PFO; Congenital heart defect - PFO

What are the causes of Patent Foramen Ovale?

A foramen ovale allows blood to go around the lungs. A baby's lungs are not used when it grows in the womb, so the hole does not cause problems in an unborn infant.

The opening is supposed to close soon after birth, but sometimes it does not. In about 1 out of 4 people, the opening never closes. If it does not close, it is called a PFO.

The cause of a PFO is unknown. There are no known risk factors. It can be found along with other heart abnormalities such as atrial septal aneurysms or Chiari network.

What are the symptoms of Patent Foramen Ovale?

Infants with a PFO and no other heart defects do not have symptoms. Some adults with PFOs also suffer from migraine headaches.

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What are the current treatments for Patent Foramen Ovale?

This condition is not treated unless there are other heart problems, symptoms, or if the person had a stroke caused by a blood clot to the brain.

Treatment most often requires a procedure called cardiac catheterization, which is performed by a trained cardiologist to permanently seal the PFO. Open heart surgery is no longer used to treat this condition unless another surgery is being performed.

Who are the top Patent Foramen Ovale Local Doctors?
Shunichi Homma
Elite in Patent Foramen Ovale
Elite in Patent Foramen Ovale

Trustees Of Columbia University In The City Of New York

622 W 168th St, 
New York, NY 
Languages Spoken:
English

Shunichi Homma is a Cardiologist in New York, New York. Dr. Homma is rated as an Elite provider by MediFind in the treatment of Patent Foramen Ovale. His top areas of expertise are Patent Foramen Ovale, Atrial Septal Defect (ASD), Emery-Dreifuss Muscular Dystrophy, Parathyroidectomy, and Patent Foramen Ovale Repair.

Gianluca Rigatelli
Elite in Patent Foramen Ovale
Elite in Patent Foramen Ovale
Monselice, IT 

Gianluca Rigatelli practices in Monselice, Italy. Mr. Rigatelli is rated as an Elite expert by MediFind in the treatment of Patent Foramen Ovale. His top areas of expertise are Patent Foramen Ovale, Atrial Septal Defect (ASD), Coronary Heart Disease, Stent Placement, and Percutaneous Coronary Intervention (PCI).

 
 
 
 
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Richard A. Krasuski
Elite in Patent Foramen Ovale
Elite in Patent Foramen Ovale

Duke Cardiology Arringdon

5601 Arringdon Park Dr, 
Morrisville, NC 
Experience:
31+ years
Languages Spoken:
English, Polish

As a fellowship trained adult congenital heart disease specialist and Director of the Adult Congenital Heart Center at Duke, I take care of a wide spectrum of heart problems, spanning from simple shunt lesions like patent foramen ovale, atrial septal defect and patent ductus arteriosus, to more complicated disorders, like tetralogy of Fallot, Ebstein anomaly, transposition of the great arteries and single ventricles. I collaborate with my colleagues in adult and pediatric medicine to provide comprehensive health services including complex cardiac interventions like catheter-based pulmonary valve implantation, closure of aortopulmonary collaterals and coarctation stenting. I am also skilled at the non-invasive and invasive assessment of patients with pulmonary hypertension. Congenital heart disease is my passion and I strive to educate my patients, their doctors and our fabulous trainees in order to improve everyone's awareness of these challenging conditions. My spare time is spent mostly at home with my wife and 2 teenage boys. I enjoy participating in and watching all types of major sports and also enjoy traveling. Dr. Krasuski is rated as an Elite provider by MediFind in the treatment of Patent Foramen Ovale. His top areas of expertise are Atrial Septal Defect (ASD), Patent Foramen Ovale, Congenital Heart Disease (CHD), Heart Transplant, and Thrombectomy.

What is the outlook (prognosis) for Patent Foramen Ovale?

An infant who has no other heart defects will have normal health and life span.

What are the possible complications of Patent Foramen Ovale?

Unless there are other defects, there are no complications from a PFO in most cases.

Some people may have a condition with shortness of breath and low arterial blood oxygen levels when sitting or standing. This is called platypnea-orthodeoxia. This is rare.

Rarely, people with PFOs may have a higher rate of a certain type of stroke (called paradoxical thromboembolic stroke). In a paradoxical stroke, a blood clot that develops in a vein (often leg veins) breaks free and travels to the right side of the heart. Normally, this clot would then continue to the lungs, but in someone with a PFO, the clot could pass through the hole to the left side of the heart. It may then be pumped out to the body, travel to the brain and become stuck there, preventing blood flow to that part of the brain (stroke).

Having a very mobile septum along with a PFO may lead to a higher risk for having a stroke.

Some people may take medicines to prevent blood clots.

When should I contact a medical professional for Patent Foramen Ovale?

Contact your health care provider if your baby turns blue when crying or having a bowel movement, has difficulty feeding, or showing poor growth.

What are the latest Patent Foramen Ovale Clinical Trials?
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study

Summary: The goal of this clinical trial is to test a new heart device called P3 Occluder System in patients who have a small opening between the upper chambers of the heart (called a Patent Foramen Ovale or PFO) and have experienced a stroke that may be related to this heart opening. The main question it aims to answer is: • Is the P3 Occluder System safe and effective for closing a PFO in patients who ha...

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

Summary: This study will assess the safety and effectiveness of GORE® CARDIOFORM Septal Occluder in a post approval setting and evaluate the quality of operator education and training and transferability of trial experience to a post-market setting.

Who are the sources who wrote this article ?

Published Date: October 23, 2023
Published By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Kliegman RM, St Geme JW, Blum NJ, Shah SS, et al. Acyanotic congenital heart disease: left-to-right shunt lesions. In: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 453.

Therrien J, Marelli AJ. Congenital heart disease in adults. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 55.

Valente AM, Dorfman AL, Babu-Narayan SV, Kreiger EV. Congenital heart disease in the adolescent and adult. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 82.