Pelvic Inflammatory DiseaseSymptoms, Doctors, Treatments, Advances & More
Pelvic Inflammatory Disease Overview
Learn About Pelvic Inflammatory Disease
Pelvic inflammatory disease (PID) is an infection of a woman's womb (uterus), ovaries, or fallopian tubes.
PID; Oophoritis; Salpingitis; Salpingo - oophoritis; Salpingo - peritonitis
PID is an infection caused by bacteria. When bacteria from the vagina or cervix travel to your womb, fallopian tubes, or ovaries, they can cause an infection.
Most of the time, PID is caused by the bacteria chlamydia or gonorrhea. These are sexually transmitted infections (STIs). Having unprotected sex with someone who has an STI can cause PID.
Bacteria normally found in the cervix can also travel into the uterus and fallopian tubes during a medical procedure such as:
- Childbirth
- Endometrial biopsy (removing a small piece of your womb lining to test for cancer)
- Getting an intrauterine device (IUD)
- Miscarriage
- Abortion
In the United States, nearly 1 million women have PID each year. About 1 in 8 sexually active women will have PID before age 20.
You are more likely to get PID if:
- You have a sex partner with gonorrhea or chlamydia.
- You have sex with many different people.
- You have had an STI in the past.
- You have recently had PID.
- You have contracted gonorrhea or chlamydia and have an IUD.
- You have had sex before age 20.
Common symptoms of PID include:
- Fever
- Pain or tenderness in the pelvis, lower belly, or lower back
- Fluid from your vagina that has an unusual color, texture, or smell
Other symptoms that may occur with PID:
- Bleeding after intercourse
- Chills
- Being very tired
- Pain when you urinate
- Having to urinate often
- Period cramps that hurt more than usual or last longer than usual
- Unusual bleeding or spotting during your period
- Not feeling hungry
- Nausea and vomiting
- Skipping your period
- Pain when you have intercourse
You can have PID and not have any severe symptoms. For example, chlamydia can cause PID with no symptoms. Women who have an ectopic pregnancy or who are infertile often have had PID caused by chlamydia. An ectopic pregnancy is when an egg grows outside of the uterus. It puts the mother's life in danger.
Your provider will often have you start taking antibiotics while waiting for your test results.
If you have mild PID:
- Your provider will give you a shot containing an antibiotic.
- You will be sent home with antibiotic pills to take for up to 2 weeks.
- You will need to follow-up closely with your provider.
If you have more severe PID:
- You may need to stay in the hospital.
- You may be given antibiotics through a vein (IV).
- Later, you may be given antibiotic pills to take by mouth.
There are many different antibiotics that can treat PID. Some are safe for pregnant women. Which type you take depends on the cause of the infection. You may receive a different treatment if you have gonorrhea or chlamydia.
Finishing the full course of antibiotics you've been given is extremely important for treating PID. Scarring inside the womb or of the tubes from PID may lead to the need to have surgery or undergo invitro fertilization (IVF) to become pregnant. Follow up with your provider after you've finished the antibiotics to make sure that you no longer have the bacteria in your body.
It's very important that you practice safer sex in order to reduce your risk of getting infections, which could lead to PID.
If your PID is caused by an STI like gonorrhea or chlamydia, your sexual partner must be treated as well.
- If you have more than one sexual partner, they must all be treated.
- If your partner is not treated, they can infect you again, or can infect other people in the future.
- Both you and your partner must finish taking all of the prescribed antibiotics.
- Use condoms until you both have finished taking antibiotics.
UPMC University Obstetrics And Gynecology
Harold C. Wiesenfeld, MD, specializes in obstetrics and gynecology and is certified in obstetrics and gynecology by the American Board of Obstetrics and Gynecology. He practices at UPMC University Obstetrics and Gynecology and UPMC Magee-Womens Gynecologic Specialties and is affiliated with UPMC Magee-Womens Hospital, UPMC Presbyterian, and UPMC Mercy. He completed his medical degree and residency at McGill University in Montreal, Canada.Dr. Wiesenfeld specializes in the care of individuals with infections of the reproductive system and people with vulvar skin disorders. He is active in clinical research to improve the diagnosis and treatment of people with these conditions and is the medical director of the Center for Vulvar and Vaginal Health at UPMC. He has published over 100 research papers and other scholarly articles.Are you already a patient of this provider and have a MyUPMC account? Log in to MyUPMC to schedule. Dr. Wiesenfeld is rated as an Elite provider by MediFind in the treatment of Pelvic Inflammatory Disease. His top areas of expertise are Pelvic Inflammatory Disease, Chlamydia, Cervicitis, Gonorrhea, and Intrauterine Device Insertion.
OHSU Hospital
Aaron Caughey is a Neonatologist and an Obstetrics and Gynecologist in Portland, Oregon. Dr. Caughey is rated as an Elite provider by MediFind in the treatment of Pelvic Inflammatory Disease. His top areas of expertise are Gestational Diabetes, Endometritis, Erb's Palsy, Intrauterine Device Insertion, and Hysterectomy.
Child And Adolescent Mental Health-Stanford Children's Health Specialty Services-Sunnyvale
Ruth Lathi is a Reproductive Medicine provider in Sunnyvale, California. Dr. Lathi is rated as an Elite provider by MediFind in the treatment of Pelvic Inflammatory Disease. Her top areas of expertise are Infertility, Endometritis, Pelvic Inflammatory Disease, Mosaicism, and Intrauterine Device Insertion.
PID infections can cause scarring of the pelvic organs. This can lead to:
- Long-term (chronic) pelvic pain
- Ectopic pregnancy
- Infertility
- Tubo-ovarian abscess
If you have a serious infection that does not improve with antibiotics, you may need surgery.
Contact your provider if:
- You have symptoms of PID.
- You think you have been exposed to an STI.
- Treatment for a current STI does not seem to be working.
Get prompt treatment for STIs.
You can help prevent PID by practicing safer sex.
- The only guaranteed way to prevent an STI is to not have sex (abstinence).
- You can reduce your risk by having a sexual relationship with only one person. This is called being monogamous.
- Your risk will also be reduced if you and your sexual partners get tested for STIs before starting a sexual relationship.
- Using a condom every time you have sex also reduces your risk.
Here is how you can reduce your risk for PID:
- Get regular STI screening tests.
- If you are a new couple, get tested before starting to have sex. Testing can detect infections that are not causing symptoms.
- If you are a sexually active woman age 24 or younger, get screened each year for chlamydia and gonorrhea.
- All women with new sexual partners or multiple partners should also be screened.
- Use of oral contraception also significantly reduces the risks of PID.
Summary: This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo. Both groups also will receive standard of care preoperative antibiotics (excluding azithromycin). The primary endpoint is a maternal infection composite defined as any one ...
Summary: This early phase I trial compares the side effects between patients treated with proton radiation therapy versus intensity modulated radiation therapy after surgery for the treatment of endometrial or cervical cancer. Radiation therapy uses high energy protons or x-rays to kill tumor cells and shrink tumors. Using quality of life questionnaires and adverse event assessments may help doctors learn ...
Published Date: August 18, 2025
Published By: LaQuita Martinez, MD, Department of Obstetrics and Gynecology, Emory Johns Creek Hospital, Alpharetta, GA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Centers for Disease Control and Prevention website. Sexually transmitted infections treatment guidelines, 2021. www.cdc.gov/std/treatment-guidelines/default.htm. Updated June 13, 2023. Accessed August 29, 2025.
Dionne JA, Marrazzo JM. Infections of the female pelvis. In: Blaser MJ, Cohen JI, Holland SM, et al, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 10th ed. Philadelphia, PA: Elsevier; 2026:chap 111.
Eckert LO, Lentz GM. Genital tract infections: vulva, vagina, cervix, toxic shock syndrome, endometritis, and salpingitis. In: Gershenson DM, Lentz GM, Valea FA, Lobo RA, eds. Comprehensive Gynecology. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 23.
Lipsky AM, Hart D. Acute pelvic pain. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 29.
Seña AC, Swygard H, Cohen MS. Approach to the patient with a sexually transmitted infection. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 264.
