Comparison Between Two Protocols for Management of Prelabor Rupture of the Membranes at Term
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Prolonged rupture of membranes has been associated with increased risk of chorioamnionitis and endometritis. In this study the investigators will investigate whether an early intervention to augment labor with oxytocin is superior to expected management for spontaneous delivery (up to 24 hours).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:
• Primiparous women with a singleton pregnancy that are admitted with prelabor rupture of membranes.
• Women at gestational age 370/7 or more.
• Vertex presentation.
Locations
Other Locations
Israel
Rambam
RECRUITING
Ramat Yishai
Contact Information
Primary
Gal Bachar, MD
gal.bachar13@gmail.com
+972524858699
Time Frame
Start Date: 2020-05-01
Estimated Completion Date: 2024-05-01
Participants
Target number of participants: 524
Treatments
Experimental: Immediate oxytocin infusion
Once the patient will arrive at the maternity ward with prelabor rupture of membranes, she will receive oxytocin for augmentation of labor.
Experimental: Expectant management for 24 hours
Once the patient will arrive at the maternity ward with prelabor rupture of membranes, we will wait for spontaneous delivery to occur. After 24 hours of rupture of membranes, the woman will receive oxytocin for augmentation of labor.
Related Therapeutic Areas
Sponsors
Leads: Rambam Health Care Campus