Assessment of Dysfunction in Left Cardiac Chambers With Strain-analyses in Patients With Lower Extremity Arterial Disease
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Single centre observational study to assess lower extremity arterial disease (LEAD) patients' cardiac dysfunction with strain analyses and to assess connections between cardiac dysfunction, metabolomic changes and target organ damage in LEAD.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 85
Healthy Volunteers: f
View:
• Fontaine I-IV class symptoms
• Confirmed diagnosis of LEAD
• Age 35-85
• Has to have at least of the following: hypertension, diabetes, coronary artery disease or the patient smokes
Locations
Other Locations
Estonia
Tartu University Hospital
RECRUITING
Tartu
Contact Information
Primary
Jaak Kals, PhD
jaak.kals@ut.ee
731 8292
Time Frame
Start Date: 2024-02-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 162
Treatments
LEAD
LEAD diagnosis confirmed by by ankle-brachial index (≤0,9 or \>1,3) or angiography. Fontaine I-IV class symptoms.
Controls
Matched with LEAD group's patients as much as possible for age, sex, smoking history, hypertension, diabetes, coronary artery disease.
Related Therapeutic Areas
Sponsors
Leads: Tartu University Hospital