Efficacy of Surgical Glove-Compression Therapy As a Prevention of Paclitaxel-Induced Peripheral Neuropathy: Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this randomized controlled trial (RCT) is to compare the incidence of paclitaxel-induced grade 2 or higher sensory peripheral neuropathy, evaluated using the CTCAE version 5.0, between patients receiving surgical glove-compression therapy (SGCT) and those in the control group. The main question is whether SGCT is effective in preventing paclitaxel-induced sensory peripheral neuropathy. * Intervention group: receive SGCT. * Control group: receive non-compressive plastic gloves.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Signed Informed Consent Form

• Age 18 years or older at the time of signing Informed Consent Form

• Patients with any pathological diagnosis of solid tumor, such as breast cancer or lung cancer

• Patients scheduled to be receiving intravenous paclitaxel or paclitaxel-based regimen every 3 weeks

Locations
Other Locations
Thailand
Rajavithi Hospital, Medical Oncology Unit
RECRUITING
Bangkok
Contact Information
Primary
Saowani Thantaviraya, M.D.
saowani.mook@gmail.com
+66805564241
Backup
Sunatee Sa-nguansai, M.D.
sunatee@hotmail.com
+66896949358
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2026-06-01
Participants
Target number of participants: 36
Treatments
Experimental: Surgical Glove-Compression Therapy
Patients wore double-layered surgical gloves, one size smaller than measured, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.
Placebo_comparator: non-compressive plastic gloves
Patients wore non-compressive plastic gloves, covered by large cotton gloves on both hands, for 30 minutes before, during, and after chemotherapy.
Related Therapeutic Areas
Sponsors
Leads: Department of Medical Services Ministry of Public Health of Thailand

This content was sourced from clinicaltrials.gov