Capillary Leak Index Versus Conventional Biomarkers in Predicting Sepsis-Related Outcomes
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
This study aims to evaluate the prognostic significance of CLI in predicting 28-day mortality and other outcomes in critically ill patients who develop post-operative abdominal sepsis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years.
• Postoperative secondary peritonitis requiring ICU admission, with clinical evidence of:
• Diffuse or localized abdominal pain/tenderness. Peritoneal signs (e.g., guarding, rigidity, rebound tenderness). Imaging or intraoperative confirmation of purulent/exudative intra-abdominal fluid.
• Systemic inflammation (e.g., fever, leukocytosis, or vasopressor requirement). Sepsis diagnosis per Sepsis-3 criteria: Suspected/confirmed infection with acute increase in SOFA score ≥2 points (6).
• Anticipated ICU stay ≥48 hours postoperatively.
Locations
Other Locations
Egypt
Benha University Hospital
RECRUITING
Banhā
Time Frame
Start Date: 2025-12-10
Estimated Completion Date: 2026-10-30
Participants
Target number of participants: 100
Treatments
adult patients admitted to the ICU with post-operative secondary peritonitis requiring an ICU stay o
Related Therapeutic Areas
Sponsors
Leads: Benha University