PFAPA
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What is the definition of PFAPA?
PFAPA is characterized by high fevers lasting three to six days and recurring every 21 to 28 days, accompanied by some or all of the signs noted in its name, namely mouth sores (aphthous stomatitis), sore throat (pharyngitis), and enlarged lymph nodes (cervical adenitis). The syndrome is sporadic and non-hereditary.
What are the alternative names for PFAPA?
  • Periodic fever, aphthous stomatitis, pharyngitis and adenitis
  • Marshall Syndrome
  • PFAPA
Who are the top PFAPA Local Doctors?
Elite in PFAPA
Michael F. Hofer
Elite in PFAPA
Michael F. Hofer
Rennaz, VD, CH 

Michael Hofer practices practicing medicine in Rennaz, Switzerland. Hofer is rated as an Elite expert by MediFind in the treatment of PFAPA. They are also highly rated in 22 other conditions, according to our data. Their clinical expertise encompasses PFAPA, Aphthous Stomatitis, Canker Sore, Juvenile Idiopathic Arthritis (JIA), and Osteotomy.

Elite in PFAPA
Donato Rigante
Elite in PFAPA
Donato Rigante
Rome, IT 

Donato Rigante practices practicing medicine in Rome, Italy. Mr. Rigante is rated as an Elite expert by MediFind in the treatment of PFAPA. He is also highly rated in 56 other conditions, according to our data. His clinical expertise encompasses PFAPA, Aphthous Stomatitis, Canker Sore, and Mevalonate Kinase Deficiency.

 
 
 
 
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Elite in PFAPA
Amra Adrovic
Elite in PFAPA
Amra Adrovic
Istanbul, TR 

Amra Adrovic practices practicing medicine in Istanbul, Turkey. Ms. Adrovic is rated as an Elite expert by MediFind in the treatment of PFAPA. She is also highly rated in 29 other conditions, according to our data. Her clinical expertise encompasses PFAPA, Scleroderma, Systemic Sclerosis (SSc), Familial Mediterranean Fever, and Adenoidectomy.

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What are the latest PFAPA Clinical Trials?
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Enrollment Status: Recruiting
Publish Date: April 08, 2026

Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood. Symptoms can include swelling of the glands in the throat, mouth ulcers, and tonsillitis. Removal of the tonsils can stop the periodic flareups. But researchers do not know how PFAPA develops. In this natural history study, researchers will collect specimens and ...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center