Learn About Piebaldism

What is the definition of Piebaldism?

Piebaldism is a condition characterized by the absence of cells called melanocytes in certain areas of the skin and hair. Melanocytes produce the pigment melanin, which contributes to hair, eye, and skin color. The absence of melanocytes leads to patches of skin and hair that are lighter than normal. Approximately 90 percent of affected individuals have a white section of hair near their front hairline (a white forelock). The eyelashes, the eyebrows, and the skin under the forelock may also be unpigmented.

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What are the causes of Piebaldism?

Piebaldism can be caused by mutations in the KIT and SNAI2 genes. Piebaldism may also be a feature of other conditions, such as Waardenburg syndrome; these conditions have other genetic causes and additional signs and symptoms.

How prevalent is Piebaldism?

The prevalence of piebaldism is unknown.

Is Piebaldism an inherited disorder?

This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

Who are the top Piebaldism Local Doctors?
Elite
Highly rated in
4
conditions

University Of Amsterdam

Amsterdam Infection And Immunity Institute, Amsterdam University Medical Center 
Amsterdam, NH, NL 

Lisa Komen is in Amsterdam, Netherlands. Komen is rated as an Elite expert by MediFind in the treatment of Piebaldism. She is also highly rated in 4 other conditions, according to our data. Her top areas of expertise are Piebaldism, Vitiligo, Hypomelanotic Disorder, and Albinism.

Distinguished
Highly rated in
12
conditions

University Of Amsterdam

Amsterdam, NH, NL 

Albert Wolkerstorfer is in Amsterdam, Netherlands. Wolkerstorfer is rated as a Distinguished expert by MediFind in the treatment of Piebaldism. He is also highly rated in 12 other conditions, according to our data. His top areas of expertise are Vitiligo, Hypomelanotic Disorder, Piebaldism, and Stork Bite.

 
 
 
 
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Distinguished
Highly rated in
30
conditions

Kindai University Faculty Of Medicine

Osaka, JP 

Naoki Oiso is in Osaka, Japan. Oiso is rated as a Distinguished expert by MediFind in the treatment of Piebaldism. He is also highly rated in 30 other conditions, according to our data. His top areas of expertise are Hypomelanotic Disorder, Pigmented Purpuric Dermatosis, Incontinentia Pigmenti, and Piebaldism.

What are the latest Piebaldism Clinical Trials?
Screening Protocol for Genetic Diseases of Allergic Inflammation
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Who are the sources who wrote this article ?

Published Date: February 01, 2013Published By: National Institutes of Health

What are the Latest Advances for Piebaldism?
Assessment of Non-cultured Autologous Epidermal Cell Grafting Resuspended in Hyaluronic Acid for Repigmenting Vitiligo and Piebaldism Lesions: A Randomized Clinical Trial.
Successful rescue of a lethal Griscelli syndrome type 2 presenting with neurological involvement and hemophagocytic lymphohistiocytosis: a case report.
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Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement.