A Physiological Study to Determine the Enteral Threonine Requirements in Infants Aged 1 to 6 Months
Status: Terminated
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is the 5th in a series of physiological studies to determine the amino acid requirements of infants. There have been 4 studies to determine tyrosine, methionine, threonine and lysine requirements in infants when they are fed by parenterally (intravenously). Due to the new requirements of Health Canada for preparation of parenteral solutions, the investigators are starting the phase of the study that determines the enteral (oral) intake of threonine in 1 - 6 mo infants in the interim.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 6 months
Healthy Volunteers: f
View:
• Between ages 1 - 6 months
• Born between 32 and 43 weeks gestational age
• Clinically stable (normal vital signs and blood values)
• Fed by nasogastric (NG), jejunal (J or NJ), or gastric (G) tube
Locations
Other Locations
Canada
The Hospital for Sick Children
Toronto
Time Frame
Start Date: 2016-02
Completion Date: 2023-10
Participants
Target number of participants: 2
Treatments
Experimental: Dietary Threonine Intake
Physiological establishment of enteral intake of amino acid threonine required by infants ages 1 - 6 mos
Related Therapeutic Areas
Sponsors
Leads: The Hospital for Sick Children