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Condition

Tracheoesophageal Fistula

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Tracheoesophageal Fistula?

Tracheoesophageal fistula (TEF) is a life-threatening condition in which there is an abnormal connection between the esophagus and trachea (windpipe). The esophagus and trachea run next to each other through the chest cavity. The esophagus carries food and saliva to the stomach, while the trachea carries air to the lungs. TEF can lead to severe and fatal lung complications. Saliva and gastric secretions can be aspirated into the lungs, and normal swallowing and digestion of food cannot occur. Most affected people are diagnosed immediately after birth or during infancy. Symptoms may include frothy bubbles of mucus in the mouth and nose; episodes of coughing and choking; and worsening symptoms during feeding. TEF may be isolated, or it may occur with other physical or developmental abnormalities (most commonly, esophageal atresia). In many cases the cause is unknown but it has been associated with some chromosome disorders. In some cases it may be acquired later in life after a cancer, infection, ruptured diverticula, or trauma. Treatment includes immediate surgical repair with survival rates of almost 100%.

What are the alternative names for Tracheoesophageal Fistula?

  • Tracheoesophageal fistula with or without esophageal atresia
  • TE fistula
  • TEF

Is Tracheoesophageal Fistula an inherited disorder?

In most cases, tracheoesophageal fistula (TEF) is not inherited and there is only one affected person in a family. When TEF is isolated (i.e. does not occur with any other abnormalities), it is considered a multifactorial condition (caused by a combination of various genetic and environmental factors). However, in most isolated cases, no specific genetic changes or environmental factors have been proven to cause the condition. When TEF occurs as a feature of a genetic syndrome or chromosome abnormality, it may follow the inheritance pattern and recurrence risk for the underlying condition. In these cases, it may be caused by changes in single genes or chromosomes, or it may be multifactorial.

Latest Research

Latest Advance
Study
  • Condition: Anastomosis Leakage Following Surgery for Esophageal Atresia and Tracheoesophageal Fistula
  • Journal: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
  • Treatment Used: Nasojejunal Catheter
  • Number of Patients: 18
  • Published —
In this study, researchers evaluated the safety and effectiveness of the placement of a nasojejunal catheter for the treatment of anastomosis leakage following surgery for esophageal atresia and tracheoesophageal fistula.
Latest Advance
Study
  • Condition: Long-Gap Esophageal Atresia
  • Journal: Medicine
  • Treatment Used: Magnetic Compression Anastomosis
  • Number of Patients: 1
  • Published —
This case report describes an infant with long-gap esophageal atresia that was treated using magnetic compression anastomosis.