Pigment-Dispersion Syndrome Treatments

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Generic Name

Bimatoprost

Brand Names

Durysta, Lumigan, Latisse, Zolymbus

FDA approval date: January 26, 2009

Classification: Prostaglandin Analog

Form: Gel, Implant, Solution

What is Durysta (Bimatoprost)?

LUMIGAN ®

Approved To Treat

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Related Clinical Trials

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Who is this study for: Patients with open-angle glaucoma or ocular hypertension

Enrollment Status: Recruiting

Publish Date: March 23, 2026

Intervention Type: Drug, Other

Study Drug: AGN-193408 SR

Study Phase: Phase 1/Phase 2

Summary: This is a multicenter, open-label, dose escalation (Cohort 1) to masked, randomized, parallel-groups (Cohort 2) and (Cohort 3) study to evaluate the safety and efficacy of AGN-193408 SR in participants with open-angle glaucoma or ocular hypertension

Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

Enrollment Status: Recruiting

Publish Date: March 05, 2026

Intervention Type: Drug

Study Phase: Phase 4

Summary: The objective of this study is to evaluate whether reduction in topical medication with the injection of a sustained release capsule (Durysta) leads to a reduction in ocular surface inflammation, indicated by levels of caspase-1, an inflammatory biomarker.

A Prospective, Multicenter, Randomized, Masked, Controlled Study to Evaluate the Safety and Efficacy of the Bimatoprost Implant System (78 mcg) Used in Combination With the SpyGlass IOL Compared to Timolol Maleate Ophthalmic Solution, USP, 0.5%,

Enrollment Status: Recruiting

Publish Date: October 20, 2025

Intervention Type: Device, Drug

Study Phase: Phase 3

Summary: This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension undergoing cataract surgery.

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