Condition 101 About Pigmented Purpuric Dermatosis

What is the definition of Pigmented Purpuric Dermatosis?

Pigmented purpuric dermatosis is a chronic condition characterized by reddish-brown skin lesions caused by leaky capillaries. Although they can arise on any part of the body, they are most commonly located on the lower legs. In some cases, the skin lesions cause severe itching. The skin lesions may spread over time, or clear up on their own. The cause of pigmented purpuric dermatosis is unknown. While treatment may not be necessary, topical steroids may help control itching. Other options for management include compression stockings, oral medications, and phototherapy.

What are the alternative names for Pigmented Purpuric Dermatosis?

  • Schamberg disease
  • Familial pigmented purpuric eruption
  • Schamberg purpura
  • Pigmented purpura
  • Progressive pigmented purpura
  • Pigmented purpuric eruption

What are the causes for Pigmented Purpuric Dermatosis?

The cause of pigmented purpuric dermatosis is unknown. Occasionally, it occurs as a reaction to a medication, food additive, viral infection or following exercise. In rare cases, there appears to be a genetic component.

What are the symptoms for Pigmented Purpuric Dermatosis?

The main features of pigmented purpuric dermatosis (PPD) are petechiae (tiny red spots due to broken blood vessels) or purpura (purple-colored spots or patches due to broken blood vessels), and yellow to brown pigmented patches. The most common sites are the legs, although lesions also may develop in other areas. Infrequently, PPD manifests as a generalized rash. The palms of the hands, soles of the feet, genitalia, and mucosa typically are not affected. Depending on the type of PPD a person has, additional signs and symptoms may include red-brown patches, plaques, linear lesions, itching, and/or other features. In general, PPD does not cause serious health problems but is a chronic condition. Signs and symptoms may persist, wax and wane, or slowly progress, and may go away over a period of months to years.

What are the current treatments for Pigmented Purpuric Dermatosis?

If the condition is mild, treatment may not be necessary. For those who suffer from itching, topical steroids and antihistamines may be useful. Compression stockings may be used if the lower legs are affected. Additional treatments that have been successful in limited studies include pentoxifylline, aminaphtone, photochemotherapy (PUVA), griseofulvin, oral cyclosporin, and ascorbic acid with rutoside.

Top Global Doctors For Pigmented Purpuric Dermatosis

Michihiro Kono
Akita, JP
Naoki Oiso
Sayama, JP
Ming F. Li
Shanghai, CN
Hee Y. Kang
Gimcheon, KR
Elisa Cinotti
Elisa Cinotti
Siena, IT
Pietro Rubegni
Pietro Rubegni
Siena, IT

Latest Advances On Pigmented Purpuric Dermatosis

  • Condition: Dermal pigmentation in Asians
  • Journal: Lasers in medical science
  • Treatment Used: Picosecond 755-nm alexandrite laser
  • Number of Patients: 26
  • Published —
The study researched the safety and effectiveness of picosecond 755-nm alexandrite laser for dermal pigmentation in Asians.
  • Condition: Actinic Keratosis
  • Journal: Journal of the American Academy of Dermatology
  • Treatment Used: Laser-Assisted Photodynamic Therapy (PDT)
  • Number of Patients: 0
  • Published —
In this review of the literature, researchers compared the effects of laser-assisted photodynamic therapy (PDT) versus conventional photodynamic therapy for the treatment of actinic keratosis.

Clinical Trials For Pigmented Purpuric Dermatosis

Clinical Trial
  • Status: Recruiting
  • Phase: N/A
  • Intervention Type: Device
  • Participants: 500
  • Start Date: June 2016
Evaluation of a New Dermal Cryotherapy System for the Treatment of Benign Pigmented Lesions
Clinical Trial
  • Status: Recruiting
  • Intervention Type: Device
  • Participants: 750
  • Start Date: October 2008
Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin