Latest Advances

  • Condition: Advanced Tenosynovial Giant Cell Tumor (TGCT)
  • Journal: Scientific reports
  • Treatment Used: Imatinib Mesylate (IM)
  • Number of Patients: 62
  • Published —
This study investigated the long term effects of imatinib mesylate (IM) in tenosynovial giant cell tumors (TGCT).
  • Condition: Malignant tenosynovial giant cell tumor
  • Journal: Anti-cancer drugs
  • Treatment Used: Chemotherapy and tyrosine-kinase inhibitors
  • Number of Patients: 0
  • Published —
The study researched multiple whole body treatments options for malignant tenosynovial giant cell tumor.
  • Condition: Tenosynovial Giant Cell Tumor (TSGCT)
  • Journal: Journal of shoulder and elbow surgery
  • Treatment Used: Surgical Resection with or without Synovectomy
  • Number of Patients: 27
  • Published —
This study compared the clinical outcome of using a surgical resection with or without a synovectomy to treat patients with TSGCT.
  • Condition: Advanced Tenosynovial giant cell tumour (TGCT)
  • Journal: Lancet (London, England)
  • Treatment Used: Pexidartinib
  • Number of Patients: 120
  • Published —
The objective of the study was to determine the effects of pexidartinib versus a test drug on patients with Advanced Tenosynovial giant cell tumour (TGCT).
  • Condition: Primary spine tumor
  • Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • Treatment Used: Computed tomography-based navigation system-assisted surgery
  • Number of Patients: 18
  • Published —
The study researched the safety and effectiveness of computed tomography-based navigation system-assisted surgery for patients with primary spine tumor.
  • Condition: Tenosynovial giant cell tumours
  • Journal: The bone & joint journal
  • Treatment Used: Surgery
  • Number of Patients: 206
  • Published —
This study evaluated the quality of life and joint function in patients with tenosynovial giant cell tumour before and after surgical treatment.
  • Condition: Diffuse Pigmented Villonodular Synovitis of the Knee
  • Journal: Archives of orthopaedic and trauma surgery
  • Treatment Used: Open Synovectomy with Adjuvant Radiosynoviorthesis (RSO)
  • Number of Patients: 32
  • Published —
This study tested the safety and efficacy of using an open synovectomy with an adjuvant RSO to treat patients with diffuse pigmented villonodular synovitis of the knee.
  • Condition: Pigmented villonodular synovitis
  • Journal: Journal of orthopaedic surgery and research
  • Treatment Used: Cementless total hip arthroplasty using ceramic-on-ceramic articulation
  • Number of Patients: 22
  • Published —
The study researched the effects of a cementless total hip arthroplasty using ceramic-on-ceramic articulation on pigmented villonodular synovitis.
  • Condition: Patients With Pigmented Villonodular Synovitis (PVNS)
  • Journal: The Journal of arthroplasty
  • Treatment Used: Total Knee Arthroplasty (TKA)
  • Number of Patients: 453
  • Published —
This study evaluated pigmented villonodular synovitis (PVNS) of the knee as a risk factor for complication after total knee arthroplasty (replacement; TKA).
  • Condition: Diffuse-Type Tenosynovial Giant-Cell Tumor of Knee (dtTGCT)
  • Journal: The bone & joint journal
  • Treatment Used: Adjuvant 90Yttrium (90Y) Hydroxyapatite
  • Number of Patients: 34
  • Published —
This study investigated the long-term outcome of patients with diffuse-type tenosynovial giant-cell tumour (dtTGCT) of the knee who underwent synovectomy with and without adjuvant treatment with 90Yttrium.
  • Condition: Locally Advanced Pigmented Villonodular Synovitis
  • Journal: The Lancet. Oncology
  • Treatment Used: Nilotinib
  • Number of Patients: 56
  • Published —
This study tested the safety and efficacy of using nilotinib to treat patients with diffuse-type giant cell tumors known as locally advanced pigmented villonodular synovitis.
  • Condition: Pigmented Villonodular Synovitis
  • Journal: The Journal of arthroplasty
  • Treatment Used: Hip Arthroplasty
  • Number of Patients: 25
  • Published —
This study tested the safety and efficacy of using a hip arthroplasty to treat patients with pigmented villonodular synovitis.
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