Learn About Pineoblastoma

What is the definition of Pineoblastoma?
Pineoblastoma is a type of cancerous (malignant) tumor that grows in a part of the brain known as the pineal gland. It occurs mainly in children. Symptoms of Pineoblastoma include a buildup of fluid around the brain (hydrocephalus), headaches, nausea, and difficulty with eye movement. The cause of Pineoblastoma is unknown, but specific inherited genetic variants in two genes, RB1 and DICER1 can increase the risk for a Pineoblastoma. Diagnosis is based on the symptoms, clinical exam, and imaging studies. In addition, a biopsy is often done to examine a small piece of tumor tissue under the microscope.
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What are the alternative names for Pineoblastoma?
  • Pineoblastoma
Who are the top Pineoblastoma Local Doctors?
CM
Carmine Mottolese
Elite
Highly rated in
17
conditions

Hôpital Femme Mère Enfant

Lyon, FR 

Carmine Mottolese is in Lyon, France. Mottolese is rated as an Elite expert by MediFind in the treatment of Pineoblastoma. He is also highly rated in 17 other conditions, according to our data. His top areas of expertise are Pineoblastoma, Pineocytoma, Plagiocephaly, and Metopic Ridge.

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JV
Joham Velasquez-Choque
Elite
Highly rated in
14
conditions

Helsinki University Hospital

Helsinki, FI 

Joham Velasquez-Choque is in Helsinki, Finland. Velasquez-Choque is rated as an Elite expert by MediFind in the treatment of Pineoblastoma. They are also highly rated in 14 other conditions, according to our data. Their top areas of expertise are Pineocytoma, Pineoblastoma, Vein of Galen Aneurysm, and Gliomatosis Cerebri.

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MM
Michelle Montange-Fevre
Elite
Highly rated in
6
conditions

Université De Lyon

Centre De Pathologie Est, Groupement Hospitalier Est 
Bron, FR 

Michelle Montange-Fevre is in Bron, France. Montange-Fevre is rated as an Elite expert by MediFind in the treatment of Pineoblastoma. She is also highly rated in 6 other conditions, according to our data. Her top areas of expertise are Pineoblastoma, Pineocytoma, Desmoplastic Small Round Cell Tumor, and Cerebral Ventricle Cancer.

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What are the latest Pineoblastoma Clinical Trials?
Pilot Study of High-Dose Chemotherapy With Busulfan, Melphalan, and Topotecan Followed by Autologous Hematopoietic Stem Cell Transplant in Advanced Stage and Recurrent Tumors
Who is this study for: Patients with advanced stage and recurrent tumors
Status: Active, not recruiting
Start Date: February 26, 2007
Intervention Type: Drug, Procedure, Biological, Other
Study Drugs: Sargramostim, Topotecan, Melphalan
Phase: Phase 1
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Summary: RATIONALE: Giving high-dose chemotherapy before an autologous stem cell transplant stops the growth of tumor cells by stopping them from dividing or killing them. Giving colony-stimulating factors, such as G-CSF, helps stem cells move from the bone marrow to the blood so they can be collected and stored. Chemotherapy is then given to prepare the bone marrow for the stem cell transplant. The stem c...
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Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor
Who is this study for: Patients with Brain and Central Nervous System Tumors
Status: Active, not recruiting
Start Date: August 2003
Intervention Type: Drug, Biological, Procedure, Radiation
Study Drugs: Cisplatin
Phase: Phase 3
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Summary: Drugs used in chemotherapy, such as vincristine, cisplatin, and cyclophosphamide, work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Combining radiation therapy with chemotherapy may kill more tumor cells. Autologous stem cell transplant may be able to replace blood-forming cells that were destroyed...
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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Pineoblastoma?
Sex-Based Differences in Treatment and Prognosis for Adult Pineoblastoma.
Journal: International journal of radiation oncology, biology, physics
Published: October 27, 2021
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Summary: Sex-Based Differences in Treatment and Prognosis for Adult Pineoblastoma.
Prognostic factors and outcome of pineoblastoma: 10 years single-center experience.
Condition: Pineoblastoma
Journal: Journal of the Egyptian National Cancer Institute
Treatment Used: Surgery, Induction Chemotherapy, and Radiation Therapy
Number of Patients: 22
Published: September 20, 2021
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Summary: Prognostic factors and outcome of pineoblastoma: 10 years single-center experience.
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Pineal teratoma with nephroblastic component in a newborn male: Case report and review of the literature.
Condition: Pineal Teratoma with Nephroblastic Component
Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Treatment Used: Staged Transcranial Approaches and Gross Total Resection
Number of Patients: 1
Published: October 25, 2020
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Summary: Pineal teratoma with nephroblastic component in a newborn male: Case report and review of the literature.
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