Pituitary Tumor Clinical Trials

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Bilateral Sphenopalatine Ganglion Block Using Prilocaine Versus Lidocaine as Adjuvants to General Anesthesia During Endoscopic Hypophysectomy, Randomized Trial.

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients undergoing endoscopic surgeries for pituitary adenoma excision suffer from wide swings in blood pressure that might increase bleeding and interfere with the surgical field. Local anethetic infiltration and regional nerve blocks have been used to provide better analgesia, control blood pressure and improve surgical field. Limited studies evaluated shenopalatine ganglion block in pituitary adenoma excision with promising outcomes. The proposed study will compare the efficacy of two local anesthetics, prilocaine and lidocaine, for spenopalatine ganglion block in patients undergoing endoscopic pituitary adenoma excision. Evaluating the control of the intraoperative blood pressure and analgesic sparing are the main objectives of the proposed study.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 45
Healthy Volunteers: f
View:

• Patients with pituitary adenoma undergoing endoscopic hypophysectomy.

• ASA physical status I and II.

• Age above 21, below 45 years.

• Male or female

Locations
Other Locations
Egypt
Kasr El Ainy
RECRUITING
Cairo
Contact Information
Primary
Rania Fahmy, Associate Professor
ransam98@gmail.com
+201270820372
Time Frame
Start Date: 2025-12-01
Estimated Completion Date: 2026-02
Participants
Target number of participants: 54
Treatments
Active_comparator: Group Lidocaine (L)
Group L will receive 2ml of 2% lidocaine and 0.5ml of diluted adrenaline.
Experimental: Group Prilocaine (P)
Group P will receive 2ml of 4% prilocaine and 0.5ml saline
Experimental: Group Prilocaine adrenaline (PA)
Group PA will receive 2ml of 4% prilocaine and 0.5ml of diluted adrenaline.
Sponsors
Leads: Kasr El Aini Hospital

This content was sourced from clinicaltrials.gov