Plaque Psoriasis Clinical Trials

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A Real-world, Longitudinal Observational Study of the Impact of Tildrakizumab on Patient Reported Outcomes in Patients With Moderate-to-severe Psoriasis in Canada

Status: Recruiting
Location: See all (6) locations...
Study Type: Observational
SUMMARY

This is a multi-centre, non-interventional, open-label, prospective observational study that will be conducted across Canada over 52-week duration. Approximately 80 patients who are initiating tildrakizumab as part of their routine care through the ILUMYA SUPPORT® Program and meet the study's eligibility criteria will be enrolled. Specifically, the study will enroll patients with Fitzpatrick scale skin types III and above. The real-world impact, safety and effectiveness of tildrakizumab on patients with moderate-to-severe plaque psoriasis (PsO) remain largely undocumented in Canada, despite its approval in 2018. Given Canada's diverse population, this study presents an opportunity to evaluate tildrakizumab's quality of life, safety and effectiveness in specific demographic groups, particularly those patients with Fitzpatrick scale skin type III and above. The findings from this study will help optimize care, address unmet needs, and ensure that treatment outcomes are inclusive and reflective of Canada's diverse population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults aged 18 years or older.

• Diagnosis of moderate-to-severe chronic plaque-type PsO with Fitzpatrick scale type III or above (BSA \>/=3%).

• Candidate for phototherapy and/or systemic therapy.

• Planning to initiate tildrakizumab as part of routine clinical care through the ILUMYA SUPPORT® Program for the treatment of plaque PsO but has not yet received their first dose.

• a. Decision to treat with tildrakizumab must be made independently of and prior to study recruitment.

• Must be able to read, understand, and communicate in English.

• Must be willing to participate in the study and capable to provide informed consent

• Able to comply with all study procedures and attend all study visits

Locations
Other Locations
Canada
Burlington Skin and Wellness
RECRUITING
Burlington
Locke Dermatology
RECRUITING
Hamilton
Panorama Dermatology Clinic
RECRUITING
Kanata
Centricity Research London Victoria Multispecialty
RECRUITING
London
Factor Dermatology
RECRUITING
Ottawa
Saskatoon Dermatology Centre
RECRUITING
Saskatoon
Time Frame
Start Date: 2025-11-25
Estimated Completion Date: 2027-05-30
Participants
Target number of participants: 80
Treatments
Study Cohort
all participants
Related Therapeutic Areas
Sponsors
Leads: Chronicle Academy

This content was sourced from clinicaltrials.gov

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