Pneumonia Clinical Trials

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Targeting Vascular INflammation in Patients With Community-Acquired Pneumonia (TIN_CAP): a Multi-centre, Prospective, Randomized Control Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The goal of this clinical trial is to learn if icosapent ethyl (Vascepa) works to lessen the amount of inflammation in adults diagnosed with Community-Acquired Pneumonia (CAP). The main question it aims to answer is: What is the effect of taking Vascepa on inflammation in the arteries in patients with CAP? Researchers will compare the drug Vascepa to a placebo (a look-alike submstance that contains no drug) to see if Vascepa works to reduce inflammation in patients with CAP. Participants wil: * take Vacscepa or a placebo twice a day for 6 months * Visit the clinic 3 times (baseline, 30 days, and 6 months) for checkups and tests

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Patients who have:

• Hospitalization with CAP (defined as pulmonary infiltration using chest imaging, in addition to other clinical symptoms including fever, cough, and sputum)

• age \> 18 years;

• given informed consent.

Locations
Other Locations
Canada
University of Ottawa Heart Institute
RECRUITING
Ottawa
Contact Information
Primary
Kevin Boczar, MD
kboczar@ottawaheart.ca
1-613-696-7000
Backup
Ashley Cowan, BScN
acowan@ottawaheart.ca
1-613-696-7000
Time Frame
Start Date: 2026-04-08
Estimated Completion Date: 2027-06
Participants
Target number of participants: 168
Treatments
Experimental: Treatment
Participants randomized to this arm will receive Vascepa for 6 months.
Placebo_comparator: Placebo
Participants randomized to this arm will receive placebo for 6 months.
Related Therapeutic Areas
Sponsors
Leads: Ottawa Heart Institute Research Corporation

This content was sourced from clinicaltrials.gov