POEMS Syndrome
Symptoms, Doctors, Treatments, Advances & More

POEMS Syndrome Overview

Definition
Alternate Names
Top Doctors
Clinical Trials
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Learn About POEMS Syndrome

What is the definition of POEMS Syndrome?

POEMS syndrome is a rare, mulitisystem disorder. POEMS stands for the disorder's features, which may include Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, and Skin changes. Signs and symptoms may include progressive sensorimotor polyneuropathy; enlarged liver, spleen, and/or lymph nodes; a disorder of the endocrine glands (often with multiple abnormalities); a monoclonal plasma cell proliferative disorder; and darkening of the skin (hyperpigmentation). Various other symptoms may also occur and may vary among affected people. The underlying cause of the disorder is not well understood.

What are the alternative names for POEMS Syndrome?

POEMS syndrome
Crow-Fukase syndrome
Polyneuropathy organomegaly
Polyneuropathy, Organomegaly, Endocrinopathy, M protein, and Skin changes syndrome

Who are the top POEMS Syndrome Local Doctors?

Elite in POEMS Syndrome

Dr. Prashant Kapoor

Hematology | Oncology

Elite in POEMS Syndrome

Dr. Prashant Kapoor

Hematology | Oncology

MN - Cancer Transplant

200 1st St SW,

Rochester, MN

507-910-0296

Languages Spoken:

English

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Prashant Kapoor is a Hematologist and an Oncologist practicing medicine in Rochester, Minnesota. Dr. Kapoor is rated as an Elite provider by MediFind in the treatment of POEMS Syndrome. He is also highly rated in 18 other conditions, according to our data. His clinical expertise encompasses Multiple Myeloma, Waldenstrom Macroglobulinemia, Primary Amyloidosis, Monoclonal Gammopathy of Undetermined Significance (MGUS), and Bone Marrow Transplant.

Elite in POEMS Syndrome

Dr. Angela Dispenzieri

Hematology

Elite in POEMS Syndrome

Dr. Angela Dispenzieri

Hematology

MN - Cancer Hematology

200 1st St SW,

Rochester, MN

507-229-0068

Languages Spoken:

English

See accepted insurances

Offers Telehealth

Angela Dispenzieri is a Hematologist practicing medicine in Rochester, Minnesota. Dr. Dispenzieri is rated as an Elite provider by MediFind in the treatment of POEMS Syndrome. She is also highly rated in 24 other conditions, according to our data. Her clinical expertise encompasses Primary Amyloidosis, POEMS Syndrome, Multiple Myeloma, Bone Marrow Transplant, and Bone Marrow Aspiration.

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Elite in POEMS Syndrome

Satoshi Kuwabara

Elite in POEMS Syndrome

Satoshi Kuwabara

Chiba, JP

Satoshi Kuwabara practices practicing medicine in Chiba, Japan. Mr. Kuwabara is rated as an Elite expert by MediFind in the treatment of POEMS Syndrome. He is also highly rated in 63 other conditions, according to our data. His clinical expertise encompasses POEMS Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy, Guillain-Barre Syndrome, Deep Brain Stimulation, and Thymectomy.

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What are the latest POEMS Syndrome Clinical Trials?

One Gene, Two Diseases: the Pathologic Role of IGLV1-44 in AL Amyloidosis and POEMS

Enrollment Status: Recruiting

Publish Date: March 04, 2026

Summary: By detailed sequence analysis and subsequent biophysical characterization of prototypic light chains, this project aims to identify sequence fingerprints in IGLV1-44 light chains leading to AL amyloidosis and POEMS syndrome. This understanding might help improve the risk stratification and early diagnosis of patients overexpressing pathologic IGLV1-44 LCs. Moreover, the development of nanobodies e...

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