Poliomyelitis Clinical Trials

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Phase IV Clinical Study Comparing the Immunogenicity and Safety of a Single-dose Poliomyelitis Vaccine (Vero Cells), Inactivated, Sabin Strains (sIPV) in Adolescents and Adults Aged 7-50 Years Versus the Primary Immunization With DTaP-IPV-Hib Pentavalent Vaccine in Infants Aged 3 Months

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The goal of this clinical study is to compare the immunogenicity and safety of one dose of sIPV in adolescents or adults aged 7-50 years with that of three doses of DTaP-IPV-Hib Pentavalent Vaccine in Infants Aged 3 Months

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 50
Healthy Volunteers: t
View:

• Healthy adolescents and adults aged 7-50 years, and healthy infants aged 3 months;

• Participants and/or their guardians are able to understand and voluntarily sign the informed consent form (for participants aged 7-17 years, both the participant and their guardian need to sign);

• Provide valid proof of identity;

• Willing and able to comply with all visit schedules, sample collections, vaccinations, and other study procedures, and remain contactable throughout the study period;

• Fertile participants and their sexual partners voluntarily adopt effective contraceptive measures from the signing of the informed consent form until 3 months after vaccination with the study vaccine, and have no plans to donate sperm or eggs.

Locations
Other Locations
China
Longxi County Center for Disease Prevention and Control, Dingxi City
RECRUITING
Dingxi
Chengguan District Center for Disease Prevention and Control, Lanzhou City
RECRUITING
Lanzhou
Zhangye Center for Disease Prevention and Control
RECRUITING
Zhangye
Contact Information
Primary
Xiaoshu Zhang
zhxs000@126.com
86-0931-8277391
Time Frame
Start Date: 2025-09-26
Estimated Completion Date: 2026-05-02
Participants
Target number of participants: 180
Treatments
Experimental: sIPV group
adolescents or adults aged 7-50 years
Active_comparator: DTaP-IPV-Hib group
infants aged 3 months old
Related Therapeutic Areas
Sponsors
Leads: Sinovac Biotech Co., Ltd

This content was sourced from clinicaltrials.gov