Cabergoline and Letrozole Compared to Letrozole Alone for Ovulation Induction in Infertile Women With Polycystic Ovary Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Combination product, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Does combined Cabergoline and letrozole increase ovulation rate What medical problems do participants have when taking drug Cabergoline and Letrozole ? Researchers will compare drug combination of Cabergoline and letrozole to letrozole alone to see combined cabergoline and letrozole works better as ovulation induction. Participants will: experimental group will receive Cabergoline and Letrozole comparator group will receive letrozole alone TVS Monitoring will be done for 3 cycle for ovarian response
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 35
Healthy Volunteers: f
View:
• PCOS patients diagnosed according to Rotterdam criteria.
• Age: 18-35 years.
• Primary or secondary subfertility.
• Selected for ovulation induction.
Locations
Other Locations
Bangladesh
Bangladesh Medical University
RECRUITING
Dhaka
Contact Information
Primary
Mst.Sumyara Khatun, MS
sumirmc09@gmail.com
+8801746046581
Backup
Nespatul Jannat, MBBS
nespatul.jannat@gmail.com
+8801731892425
Time Frame
Start Date: 2025-02-07
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 72
Treatments
Experimental: Experimental arm : Cabergoline and letrozole
participants will receive Tab. cabergoline 0.5 mg 1 tablet at night, two dose at weekly interval (day 2 and day 9 of menstruation/withdrawal bleeding) plus tab. letrozole 5 mg/day at night from day 2 menstruation/withdrawal bleeding for 5 days for consecutive 3 cycles.
Active_comparator: Comparator arm : letrozole
participants will receive Tab. letrozole 5 mg/day at night from day 2 of menstruation/withdrawal bleeding for 5 days for consecutive 3 cycles.
Related Therapeutic Areas
Sponsors
Collaborators: Bangladesh Medical University
Leads: Mst.Sumyara Khatun