PolymicrogyriaSymptoms, Doctors, Treatments, Advances & More
Learn About Polymicrogyria
Polymicrogyria is characterized by abnormal development of the brain before birth. The surface of the brain normally has many ridges or folds, called gyri. In people with polymicrogyria, the brain develops too many folds, and the folds are unusually small. The name of this condition literally means too many (poly-) small (micro-) folds (-gyria) on the surface of the brain.
In most people with polymicrogyria, the cause of the condition is unknown. However, researchers have identified several environmental and genetic factors that may contribute to the development of this disorder.
Although the prevalence of polymicrogyria is unknown, it is one of the most common malformations of cortical development, which are malformations that affect the development of the outer surface of the brain (cerebral cortex).
It can be difficult to determine the cause and inheritance pattern of polymicrogyria. The condition can be inherited in different ways depending on the particular cause.
M Health Fairview Explorer Pediatric Specialty Clinic
William Dobyns is a Pediatrics specialist and a Neurologist practicing medicine in Minneapolis, Minnesota. He has been practicing medicine for over 48 years. Dr. Dobyns is rated as an Elite provider by MediFind in the treatment of Polymicrogyria. He is also highly rated in 51 other conditions, according to our data. His clinical expertise encompasses Increased Head Circumference, Lissencephaly, Cerebellar Hypoplasia, and Cortical Dysplasia. Dr. Dobyns is board certified in Clinical Genetics And Genomics: American Board Of Medical Genetics And Genomics, 1987. Dr. Dobyns is currently accepting new patients.
Dina Amrom practices practicing medicine in Brussels, Belgium. Ms. Amrom is rated as an Elite expert by MediFind in the treatment of Polymicrogyria. She is also highly rated in 19 other conditions, according to our data. Her clinical expertise encompasses Polymicrogyria, Rasmussen Encephalitis, Subcortical Band Heterotopia, and Miller-Dieker Syndrome.
Nadia Buisson-Bahi practices practicing medicine in Paris, France. Ms. Buisson-Bahi is rated as an Elite expert by MediFind in the treatment of Polymicrogyria. She is also highly rated in 30 other conditions, according to our data. Her clinical expertise encompasses Agyria Pachygyria Polymicrogyria, Lissencephaly, Focal or Multifocal Malformations in Neuronal Migration, and Polymicrogyria.
Summary: This is a 3-part Phase 2 randomized study evaluating the safety and efficacy of the mutant-selective PI3Kα inhibitor, zovegalisib (RLY-2608), in adults and children with PIK3CA Related Overgrowth Spectrum (PROS) and malformations driven by PIK3CA mutation. Part 1 is a dose selection, Part 2 is a basket design with exploratory single-arm cohorts for various subpopulations of participants, and Part ...
Summary: Dr. Elliott Sherr and his collaborators at University of California, San Francisco (UCSF) are studying the genetic causes of disorders of cognition and epilepsy, in particular disorders of brain development that affect the corpus callosum, such as Aicardi syndrome, as well as two additional brain malformations, polymicrogyria and Dandy-Walker malformation. The goal of the investigators' research i...
Published Date: June 16, 2026
Published By: National Institutes of Health