Polymyositis Overview

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Learn About Polymyositis

What is the definition of Polymyositis?
Polymyositis is a type of inflammatory myopathy, which refers to a group of muscle diseases characterized by chronic muscle inflammation and weakness. The muscles affected by Polymyositis are the skeletal muscles (those involved with making movements) on both sides of the body. The disease is more common among women and among black individuals. The exact cause of Polymyositis is unknown. The disease shares many characteristics with autoimmune disorders, which occur when the immune system mistakenly attacks healthy body tissues. In some cases, the disease may be associated with viral infections, connective tissue disorders, or an increased risk for malignancies (cancer). Diagnosis is based on a clinical examination that may include laboratory tests, imaging studies, electromyography, and a muscle biopsy.
What are the alternative names for Polymyositis?
  • Polymyositis
Who are the top Polymyositis Local Doctors?
Andrew L. Mammen
Elite in Polymyositis
Dr. Andrew L. Mammen
Neurology
Elite in Polymyositis
Dr. Andrew L. Mammen
Neurology
4940 Eastern Ave, 
Baltimore, MD 
Recognized by The Myositis Association
410-550-5624
Languages Spoken:
English
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Andrew Mammen is a Neurologist in Baltimore, Maryland. Dr. Mammen is rated as an Elite provider by MediFind in the treatment of Polymyositis. His top areas of expertise are Myositis, Polymyositis, Dermatomyositis, and Necrotizing Myopathy (NM).

Ingrid E. Lundberg
Elite in Polymyositis
Ingrid E. Lundberg
Rheumatology
Elite in Polymyositis
Ingrid E. Lundberg
Rheumatology
Stockholm, AB, SE 
Recognized by The Myositis Association

Ingrid Lundberg is a Rheumatologist in Stockholm, Sweden. Ms. Lundberg is rated as an Elite expert by MediFind in the treatment of Polymyositis. Her top areas of expertise are Polymyositis, Dermatomyositis, Myositis, and Antisynthetase Syndrome.

 
 
 
 
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Julie J. Paik
Elite in Polymyositis
Dr. Julie J. Paik
Rheumatology
Elite in Polymyositis
Dr. Julie J. Paik
Rheumatology

Johns Hopkins Bayview Medical Center

5501 Hopkins Bayview Circle, Floor 1, 
Baltimore, MD 
Recognized by The Myositis Association
443-997-1552
Languages Spoken:
English
See accepted insurances
Accepting New Patients
Offers Telehealth

Julie Paik is a Rheumatologist in Baltimore, Maryland. Dr. Paik is rated as an Elite provider by MediFind in the treatment of Polymyositis. Her top areas of expertise are Dermatomyositis, Polymyositis, Myositis, and Scleroderma. Dr. Paik is currently accepting new patients.

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What are the latest Polymyositis Clinical Trials?
A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Who is this study for: Adult patients with Metastatic or Unresectable Solid Tumors
Enrollment Status: Recruiting
Publish Date: October 15, 2025
Intervention Type: Procedure, Biological
Study Drug: Nivolumab
Study Phase: Phase 1

Summary: This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and sprea...

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A PHASE 3, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06823859 IN PARTICIPANTS WITH ACTIVE IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH ACTIVE DERMATOMYOSITIS OR POLYMYOSITIS)
A PHASE 3, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF PF-06823859 IN PARTICIPANTS WITH ACTIVE IDIOPATHIC INFLAMMATORY MYOPATHIES (INCLUDING PARTICIPANTS WITH ACTIVE DERMATOMYOSITIS OR POLYMYOSITIS)
Enrollment Status: Recruiting
Publish Date: October 14, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: The purpose of the study is to understand how the study medicine PF-06823859 (dazukibart) works in people with idiopathic inflammatory myopathies (DM and PM). These disorders cause inflammation that weakens the muscles that are important for movement and may also cause skin rash in people with DM. This study is seeking participants who: * Are 18 years of age or older or minimum legal adult age as ...

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Who are the sources who wrote this article ?

Published Date: May 13, 2022
Published By: Genetic and Rare Diseases Informnation Center