Variable Pulse Transcranial Magnetic Stimulation for Treatment of Post COVID Syndrome

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Patients who have had a recent episode of COVID-19 and who present to the Post COVID-19 Clinic at Mayo Clinic Rochester with at least one of the PCC symptoms of interest - anosmia, tinnitus, fatigue. Symptoms consistent with PCC lasting at least 1 month after the positive test date. Subjects must have ongoing symptoms for \> 4 weeks following the start of an acute covid infection. This is consistent with the CDC definition for post covid conditions. Start date is determined by date of first positive COVID test. There is no limitation of maximum time from acute infection start.

• At least one of the PCC symptoms of interest:

‣ Anosmia: Olfactory Threshold Test scores corresponding to Anosmia or Hyposmia

⁃ Tinnitus: \>0 score on Tinnitus Handicap Inventory (not present prior to SARS-COVID 2 infection)

⁃ Fatigue: Total Modified Fatigue Impact Scale (MFIS) Score of 40 or above

Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Department of Medicine Research Hub, Coordinator
domresearchhub@mayo.edu
507-266-1944
Time Frame
Start Date: 2025-07-22
Estimated Completion Date: 2027-04
Participants
Target number of participants: 40
Treatments
Experimental: Anosmia
Subjects Olfactory Threshold Test scores correspond to Anosmia or Hyposmia
Experimental: Tinnitus
Subjects have \>0 score on Tinnitus Handicap Inventory (not present prior to COVID infection)
Experimental: Fatigue
Subjects have Total Modified Fatigue Impact Scale (MFIS) Score of 40 or above
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic

This content was sourced from clinicaltrials.gov