Variable Pulse Transcranial Magnetic Stimulation for Treatment of Post COVID Syndrome
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).
• Patients who have had a recent episode of COVID-19 and who present to the Post COVID-19 Clinic at Mayo Clinic Rochester with at least one of the PCC symptoms of interest - anosmia, tinnitus, fatigue. Symptoms consistent with PCC lasting at least 1 month after the positive test date. Subjects must have ongoing symptoms for \> 4 weeks following the start of an acute covid infection. This is consistent with the CDC definition for post covid conditions. Start date is determined by date of first positive COVID test. There is no limitation of maximum time from acute infection start.
• At least one of the PCC symptoms of interest:
‣ Anosmia: Olfactory Threshold Test scores corresponding to Anosmia or Hyposmia
⁃ Tinnitus: \>0 score on Tinnitus Handicap Inventory (not present prior to SARS-COVID 2 infection)
⁃ Fatigue: Total Modified Fatigue Impact Scale (MFIS) Score of 40 or above