Post-Traumatic Stress Disorder (PTSD) Clinical Trials

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MOCHA Protocol: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY

Pregnant and postpartum patients hospitalized for medical complications experience high rates of depression, anxiety, and trauma-related symptoms, yet access to timely psychiatric care during obstetric hospitalization is limited. Project MOCHA integrates early mental health screening, trauma-informed psychotherapy, and structured follow-up into routine inpatient maternity care for individuals at elevated clinical risk. This single-arm implementation study examines the feasibility, acceptability, and fidelity of delivering a Collaborative Mental Health Care Program within a high-risk obstetric inpatient setting. The program includes brief inpatient psychotherapy, symptom monitoring, and post-discharge follow-up over three months. Preliminary changes in depression, anxiety, attention-deficit hyperactivity disorder, and posttraumatic stress symptoms will be assessed to inform future effectiveness trials and broader health system integration.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

• 18 years old or older

• Pregnant (or recently have given birth) at any gestational age

• Must have experienced at least one adverse pregnancy outcome

• Admitted for an extended inpatient stay

• English speaking

Locations
United States
Indiana
Riley Hospital for Children at Indiana University Health
RECRUITING
Indianapolis
Contact Information
Primary
Tiffany R Williams, PhD
tw84@iu.edu
317-963-7300
Time Frame
Start Date: 2026-07-15
Estimated Completion Date: 2027-09-01
Participants
Target number of participants: 50
Treatments
Prospective MOCHA Cohort
Perinatal patients admitted to the Riley Maternity Tower for medically complex pregnancies who receive the Collaborative Mental Health Care Program (CMHCP). Participants are followed prospectively from inpatient admission through 3-month post-discharge follow-up.
Sponsors
Leads: Indiana University

This content was sourced from clinicaltrials.gov