Posterior fossa tumor is a type of brain tumor located in or near the bottom of the skull.
Infratentorial brain tumors; Brainstem glioma; Cerebellar tumor
The posterior fossa is a small space in the skull, found near the brainstem and cerebellum. The cerebellum is the part of the brain responsible for balance and coordinated movements. The brainstem is responsible for controlling vital body functions, such as breathing.
If a tumor grows in the area of the posterior fossa, it can block the flow of spinal fluid and cause increased pressure on the brain and spinal cord.
Most tumors of the posterior fossa are primary brain cancers. They start in the brain, rather than spreading from somewhere else in the body.
Posterior fossa tumors have no known causes or risk factors.
Symptoms occur very early with posterior fossa tumors and may include:
Symptoms from posterior fossa tumors also occur when the tumor damages local structures, such as the cranial nerves. Symptoms of cranial nerve damage include:
Most tumors of the posterior fossa are removed with surgery, even if they are not cancerous. There is limited space in the posterior fossa, and the tumor can easily press on delicate structures if it grows.
Depending on the type and size of the tumor, radiation treatment may also be used after surgery.
Murali Chintagumpala is a Pediatric Hematologist Oncology specialist and a Hematologist in Houston, Texas. Chintagumpala is rated as an Elite expert by MediFind in the treatment of Posterior Fossa Tumor. He is also highly rated in 19 other conditions, according to our data. His top areas of expertise are Medulloblastoma, Gliomatosis Cerebri, Brain Tumor, and Posterior Fossa Tumor. Chintagumpala is currently accepting new patients.
Maryam Fouladi is a Pediatric Hematologist Oncology specialist and a Hematologist in Cincinnati, Ohio. Fouladi has been practicing medicine for over 32 years and is rated as an Elite expert by MediFind in the treatment of Posterior Fossa Tumor. She is also highly rated in 15 other conditions, according to our data. Her top areas of expertise are Diffuse Midline Glioma H3 K27M-Mutant, Brain Tumor, Glioma, and Medulloblastoma. Fouladi is currently accepting new patients.
Andrey Korshunov practices in Heidelberg, Germany. Korshunov is rated as an Elite expert by MediFind in the treatment of Posterior Fossa Tumor. He is also highly rated in 18 other conditions, according to our data. His top areas of expertise are Medulloblastoma, Gliomatosis Cerebri, Embryonal Tumor with Multilayered Rosettes, and Glioma.
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A good outlook depends on finding the cancer early. A total blockage in the flow of spinal fluid can be life threatening. If tumors are found early, surgery can lead to long-term survival.
Complications may include:
Call your health care provider if you have regular headaches that occur with nausea, vomiting, or vision changes.
Summary: This phase II trial determines if the combination of ONC201 with different drugs, panobinostat or paxalisib, is effective for treating patients with diffuse midline gliomas (DMGs). Despite years of research, little to no progress has been made to improve outcomes for patients with DMGs, and there are few treatment options. ONC201, panobinostat, and paxalisib are all enzyme inhibitors that may stop...
Summary: This phase I/II trial tests the safety, side effects, and best dose of selinexor given in combination with standard radiation therapy in treating children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG) or high-grade glioma (HGG) with a genetic change called H3 K27M mutation. It also tests whether combination of selinexor and standard radiation therapy works to shrink...
Published Date: January 25, 2022
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Arriaga MA, Brackmann DE. Neoplasms of the posterior fossa. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 179.
Dorsey JF, Salinas RD, Dang M, et al. Cancer of the central nervous system. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 63.
Zaky W, Ater JL, Khatua S. Brain tumors in childhood. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 524.
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