The COPENHAGEN School Study. Normal Pubertal Development in Youth 2021 and Long-term Disease and Death Risk After Extremely Early Puberty
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The COPENHAGEN School Study is a combined cross-sectional and longitudinal study of healthy Danish school children. This study will by clinical examinations and withdrawal of blood samples investigate whether age of pubertal onset is continuing to decline in Denmark over the past 15 years. Furthermore, we will investigate the mechanism driving earlier onset of puberty and the long term health risks of extremely early puberty using Danish registry data
Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 19
Healthy Volunteers: t
View:
• Healthy children and adolescents
Locations
Other Locations
Denmark
Rigshospitalet, Department of Growth and Reproduction
RECRUITING
Copenhagen
Contact Information
Primary
Anders Juul, PhD, DMSc
anders.juul@regionh.dk
+45 35 45 13 77
Time Frame
Start Date: 2023-01-01
Estimated Completion Date: 2056-12-31
Participants
Target number of participants: 3000
Treatments
Cross-sectional cohort
Healthy children and adolescents from twenty-five selected schools in the metropolitan area
Longitudinal cohort
Cases with first-time diagnoses of extremely early puberty within the period 1995-2019 in the National Patient Registry and five randomly selected references drawn from the general background population in the Danish Civil registry (CPR) matched on age and sex for each case
Related Therapeutic Areas
Sponsors
Collaborators: Environmental Protection Agency (EPA), European Commission
Leads: Rigshospitalet, Denmark